Growth of E18 rat hippocampal neuronal cells on nanostructured surfaces for enhanced electrical stimulation and recording.

We have prepared gold nanowire arrays inside nanoporous alumina templates with the goal towards neuronal interfacing and electrical recording from neurons. We have investigated biofunctionalization of such gold nanowire arrays (GNWs) and gold nanofilm (GNF) platforms to understand its impact on neuronal attachment and growth. Poly-D-Lysine (PDL) was coated on the nano-templates surfaces for adhesion of neurons which also enhanced the neuronal growth.