Publications by authors named "Mohammed A Zayed"

Article Synopsis
  • CMMRD syndrome is a serious and rare genetic disorder causing multiple cancers due to mutations in mismatch repair genes, leading to a poor prognosis.
  • The first reported case in the Gulf region involves a 13-year-old girl with advanced juvenile rectal cancer, presenting with concerning symptoms and previously undiagnosed genetic factors.
  • After receiving neoadjuvant chemoradiotherapy and undergoing major surgical procedures, the family opted out of additional therapy but chose to participate in monitoring and genetic testing, highlighting the difficulties clinicians face with rare syndromes like CMMRD.
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BACKGROUND There is a recognized association between synchronous and metachronous colorectal and gastric adenocarcinoma. This report describes a 66-year-old man presenting with port-site metastatic gastric adenocarcinoma 4 years after laparoscopic resection of a rectal adenocarcinoma. CASE REPORT A 66-year-old male rectal cancer survivor presented to the clinic with a painless mass at the previous laparoscopic anterior resection port site.

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Liver anomalies are uncommon. We are reporting a case of 27 years old male admitted as a case of biliary pancreatitis. Upon hospitalization work-up, MRCP was done reveling incidentally in situ liver malrotation which was confirmed intraoperatively.

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BACKGROUND Synchronous primary tumors are defined as 2 or more different histological tumors discovered in one patient at the same time or within a period of 6 months. Colorectal cancer is one of the most common cancers in the United States. Inversely, synchronous colorectal cancer and carcinoid tumors are rare.

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BACKGROUND Neuroendocrine neoplasms (NENs) originate from cells of the endocrine and nervous systems, and they are rarely encountered in colorectal cases with no specific symptoms. The incidence and prevalence of NENs of the large bowel are increasing. Malignant colonic types are known to have poor diagnosis.

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Introduction: Pseudomyxoma peritonei (PMP) is a feared complication of appendicular mucocele perforation. Although a rare disease, its major sequel mandates recognition and early intervention. Intestinal malrotation is mostly asymptomatic in adults.

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Adalimumab is a human monoclonal antibody which targets tumor necrosis factor (TNF)-alpha. It is produced by recombinant DNA technology, using a mammalian cell expression system and is widely-known to treat a number of immune-mediated conditions, including psoriasis. There has been a growing concern regarding the possible association between TNF-alpha inhibitors and malignancy.

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