First report of serological, molecular detection, and characterization of human parvovirus B19 infections among sickle cell anaemia patients in Khartoum State, Sudan.

Background: Patients with haematological disorders, such as sickle cell anaemia, are at an elevated risk of transient aplastic crisis due to parvovirus B19 infection. The virus targets specific integration sites in the human genome, disrupting cellular division. However, the molecular mechanisms of infection remain poorly understood.