Publications by authors named "Mohammed A Chaudry"

Background: Radical surgery for esophageal cancer requires macroscopic and microscopic clearance of all malignant tissue. A critical element of the procedure is achieving a negative circumferential margin (CRM) to minimize local recurrence. The utility of minimally invasive surgery poses challenges in replicating techniques developed in open surgery, particularly for hiatal dissection in esophago-gastrectomy.

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Article Synopsis
  • The COVID-19 pandemic significantly impacted patient care, leading to temporary halts in essential cancer surgeries, with heightened concerns about risks during the reintroduction of complex surgical procedures.
  • An international study analyzed 158 patients undergoing open and minimally invasive oesophago-gastric surgeries across nine European centers during a high COVID-19 incidence period, focusing on 30-day COVID-19-related mortality and staff health.
  • Findings indicated no post-operative COVID-19 cases among patients, though two healthcare workers experienced mild symptoms, suggesting that implemented safety measures were effective in minimizing infection risks during surgeries.
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Background And Objectives: The aim of surgical treatment of gastrointestinal stromal tumors (GIST) is a microscopically complete resection. Initial indications for laparoscopic surgery were limited to smaller tumors, in favorable locations. Over time, indications for minimal invasive surgery (MIS) have expanded, however concerns remain when considering resection of larger GISTs.

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Case Report: We report a case of an epidermoid cyst within an intrapancreatic accessory spleen that was treated by laparoscopic excision. A 39-year-old man with no abdominal symptoms was incidentally found to have a cystic pancreatic lesion on computed tomography scan undertaken for suspected deep vein thrombosis. Further computed tomography and magnetic resonance imaging confirmed similar findings and the laparoscopic resection of the distal pancreas and spleen was undertaken as malignancy could not be excluded.

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Purpose: We investigated the hypothesis that there is an "aggressive" subtype of Crohn's disease characterized by early recurrence and that disease location and surgical procedure are associated with differing patterns of recurrence.

Methods: We analyzed 280 patient records totaling 482 major abdominal operations from a prospectively compiled Crohn's disease database. Patterns of recurrence, as defined by reoperation, were analyzed by Kaplan-Meier plots and log-rank tests for the group as a whole, as well as according to disease location and operation performed using log-rank and Cox regression analysis.

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