The anticancer activity of fucoidan coated selenium nanoparticles and curcumin nanoparticles against colorectal cancer lines.

Cancers still globally endanger millions of people yearly; the incidences/mortalities of colorectal cancers are particularly increasing. The natural nanoparticles (NPs) and marine biopolymers were anticipated to provide effectual safe significances for managing cancers. The transformation of curcumin to nano-curcumin (NCur) was conducted with gum Arabic.

Lipopeptides from Bacillus atrophaeus MCM61 and melatonin suppress gray mold-induced oxidative stress in cut roses (Rosa hybrida L.) and improve vase life.

Application of melatonin and lipopeptides (LPs) derived from Bacillus strains is considered an efficient strategy to control plant diseases at both pre and postharvest stages. However, the combined application of melatonin and LPs has not been studied yet. Therefore, the present study presents the synergistic effect of melatonin and LPs produced by Bacillus atrophaeus strain MCM61 against gray mold disease and its impact on quality parameters and vase life of cut roses.

-Glycosidase Inhibition and In Silico Studies of Flavonoids Isolated from Stew ex Brandis.

The galls of are used in folk medicine for curing diabetes. The main aim of this study was the purification of flavonoids from galls of The methanolic extract was subjected to column chromatographic analysis which afforded six flavonoids, namely, 3,5,7,4'-tetrahydroxy-flavanone (1), naringenin (2), 3,5,4'-trihydroxy,7-methoxy-flavanone (3), sakuranetin (4), spinacetin (5), and patuletin (6). These isolated compounds (1-6) were tested against -glycosidase.

Nile crab Potamonautes niloticus shell extract: Chromatographic and molecular elucidation of potent antioxidant and anti-inflammatory capabilities.

Diseases emerging from oxidative stress and inflammatory imbalance are deeply threatening the modern world. Fisheries by-products are rich in bioactive metabolites. However, they are usually discarded, posing a real environmental burden.

In Vivo Anti-Inflammatory, Analgesic, Muscle Relaxant, and Sedative Activities of Extracts from (L.) Skeels in Mice.

In the current study, the folklore medicine, , was experimentally evaluated for anti-inflammatory, analgesic, sedative, and muscle relaxant effects. The extract and fractions of were found safe up to 1000 mg/kg with no mortality, except for slight sedation as a minor side effect. Both, the extract and various fractions of demonstrated significant inhibition (86.

Bovine serum albumin functionalized blue emitting Ti C MXene quantum dots as a sensitive fluorescence probe for Fe ion detection and its toxicity analysis.

In the present work, an improved class of protein functionalized fluorescent 2D Ti C MXene quantum dots (MXene QDs) was prepared using a hydrothermal method. Exfoliated 2D Ti C sheets were used as the starting precursor and transport protein bovine serum albumin (BSA) was used to functionalize the MXene QDs. BSA-functionalized MXene QDs exhibited excellent photophysical property and stability at various physiological parameters.

Antioxidant and Cytotoxic Activity of a New Ferruginan A from : and Studies.

Studies of the ethyl acetate extract bark extract of led to the isolation of one new compound Ferruginan A (1) in addition to two known compounds, Ferruginan (2) and cycloolivil (3). Structures of the isolated compounds were confirmed by mass spectrometry (MS) and NMR spectral data. The ethyl acetate fraction and compounds (1-3) were evaluated against breast cancer cell line (MCF-7) and as antioxidants using the free radical scavenging assay.

Khat Chewing and Lipid Profile in Human and Experimental Animals.

Background: , also known as khat or qat, is a plant that grows in East Africa and southern Arabia. Several millions of people chew the leaves and twigs of khat plant for their central stimulating amphetamine-like effects. Khat chewing is becoming more common in Europe and the United States, owing to worldwide migration.

Comparison of the Efficiency of , , and Methanolic Extracts in Relieving Hyperglycemia and Hyperlipidemia of Streptozotocin-Induced Diabetic Rats.

Background: Diabetes mellitus (DM) is a metabolic disorder characterized by high blood glucose levels that occurs either due to insufficient insulin production or mounting resistance to its action. The purpose of this study was to investigate if methanolic extracts of seeds, , and leaves had any effect on blood sugar levels in normal and streptozotocin (STZ) diabetic rats, as well as to explore the most effective extract.

Method: Healthy male albino rats weighing 185-266 g were divided into nine groups of eight rats each: normal control, diabetic control, diabetic rats with dietary supplements of , , and methanolic extracts, and diabetics treated with insulin.

Antidiabetic Activity of Ficusonolide, a Triterpene Lactone from (Wall. ex Miq.): , , and Approaches.

Diabetes is a chronic condition which is locally managed through the stem of . To find the exact chemical constituent responsible for this activity, a triterpene lactone (ficusonolide) isolated from was studied for antidiabetic potential through the antidiabetic paradigm employing L-6 cells and an antidiabetic assay against non-insulin-dependent rats. The results on glucose uptake in the L-6 cell line indicated that ficusonolide has enhanced the uptake of glucose by 53.

Screening of Polyphenols in Tobacco () and Determination of Their Antioxidant Activity in Different Tobacco Varieties.

Tobacco () is an herbaceous plant originating from South America and processed into cigarettes for consumption. Polyphenols are considered vital components of tobacco in view of their contribution to antioxidant properties. This study aimed to determine the phenolic compounds in different tobacco varieties by applying cold extraction with methanol and distilled water.

Association between qat chewing and dyslipidaemia among young males.

Objectives: This study investigated the association between qat chewing and prevalence and patterns of dyslipidaemia among young Yemeni males.

Methods: In this cross-sectional study, we used a multistage random cluster sampling method. Data were obtained using a questionnaire.

Augmented anticancer activity of curcumin loaded fungal chitosan nanoparticles.

Fungal chitosan (FCt) from Amylomyces rouxii, with 88.7% deacetylation degree and 112.4 kDa molecular weight, was utilized for nanoparticles (NPs) formation via ionic gelation.

Augmented control of drug-resistant Candida spp. via fluconazole loading into fungal chitosan nanoparticles.

Fungal chitosan (ACT) extraction from Amylomyces rouxii, its transforming into nano-form, loading with fluconazole (Flu) and evaluation of synthesized nanoconjugates against drug-resistant (DR) Candida spp., were investigated. The produced ACT was characterized with 112.

Prevalence of dyslipidemia among students of a Yemeni University.

Objectives: To estimate the prevalence of dyslipidemia and patterns of lipid profile and associated factors among Yemeni university students.

Methods: This cross-sectional study included 240 Yemeni students (116 males and 124 females) at Ibb University. The students were randomly selected from various faculties of the university.

Analysis of patients with end-stage renal disease on dialysis in Tabuk City, Saudi Arabia: A single-center, three-year retrospective study.

This study was performed to analyze various demographic data such as age, gender, nationality, status of the patients, and the causes of end-stage renal disease (ESRD) of 349 patients who were undergoing hemodialysis (HD) during the period from January 2013 to December 2015 at the Dialysis Center of King Khalid Hospital in Tabuk City. One hundred and fifty-two patients (43.6%) were on HD in 2015.