Publications by authors named "Mohammadreza Jafarinasab"

Article Synopsis
  • The study aimed to evaluate the short-term outcomes of a modified Boston keratoprosthesis device (ORC-KPro) in patients suffering from end-stage corneal blindness.
  • It included 12 patients (mostly middle-aged and male) where corneal blindness was primarily due to chemical burns or previous graft failures, achieving anatomical success for all cases.
  • While most patients experienced improved vision post-surgery, functional success was restricted because of underlying severe eye conditions, impacting overall visual potential.
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The ectatic disease of the cornea poses a significant challenge for ophthalmologists because commonly used treatments to improve visual acuity, such as spectacles and contact lenses, may not be effective, especially in advanced stages. In addition, the preferred surgical management, corneal transplantation, has various issues related to tissue availability, the steep learning curve, and postoperative complications such as tissue stability and half-life. Ongoing research for an alternative to keratoplasty has suggested various methods, such as corneal crosslinking, which can improve visual function when combined with other techniques.

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Purpose: The purpose of this study was to investigate the long-term clinical outcome of keratolimbal allograft (KLAL) alone or in combination with keratoplasty, in the management of patients with chronic and delayed-onset mustard gas keratopathy (MGK).

Methods: Patients who had KLAL for MGK with or without corneal transplantation between 2002 and 2016 were recalled to be enrolled in this retrospective interventional case series. The primary outcome was the success rate of the KLAL demonstrated by Kaplan-Meier cumulative survival analysis.

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Purpose: To determine the indications and surgical outcomes of intraocular lens (IOL) exchange in pseudophakic patients at Labbafinejad Tertiary Referral Center between 2014 and 2019.

Methods: In this retrospective interventional case series, the medical records of 193 patients with a history of IOL exchange were reviewed. Preoperative data, including clinical characteristics, indications of the first and second IOL implantation, intra- and postoperative complications due to IOL exchange, and the pre-and postoperative refractive error and best-corrected visual acuity (BCVA) were considered the outcome measures in this study.

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Purpose: To investigate and optimize the accuracy of aphakic refraction (AR) techniques for secondary intraocular lens (IOL) power calculation in aphakic children.

Methods: Thirty-three aphakic eyes of 18 patients who were candidates for secondary IOL implantation were enrolled in the present study. Axial length (AL) measured by optical biometry was used in the biometric formula (SRK-T, Holladay II, and Hoffer-Q).

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We describe a modified allogenic intrastromal lenticule implantation technique for management of keratoconus (KCN). Patients with advanced KCN already scheduled for corneal transplantation were enrolled. An allogenic corneal lenticule was implanted inside a stromal pocket created by femtosecond laser.

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Purpose: To report the preliminary results of a new surgical modality for the treatment of primary corneal ectasia, which consists of implanting allogeneic corneal tissue into the peripheral corneal stroma using a femtosecond laser system or femtosecond laser-assisted peripheral allogeneic stromal additive keratoplasty or FA-PASAK.

Methods: This prospective, noncomparative case series includes patients with primary corneal ectasia including keratoconus and pellucid marginal degeneration. In the operating room, one or two ring or crescent-shaped allogeneic corneal segments were prepared using a handmade double-bladed punch, which were then implanted by a specially designed device, into stromal channels in the peripheral recipient cornea fashioned with a femtosecond-laser system.

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Purpose: To investigate the indications, clinical outcomes, and complications of secondary piggyback intraocular lens (IOL) implantation for correcting residual refractive error after cataract surgery.

Methods: In this prospective interventional case series, patients who had residual refractive error after cataract surgery and were candidates for secondary piggyback IOL implantation between June 2015 and September 2018 were included. All eyes underwent secondary IOL implantation with the piggyback technique in the ciliary sulcus.

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Purpose: To investigate the efficacy of topical (AV) gel-derived eye drops on the healing of alkali-burned corneas in rabbits.

Methods: Thirty alkali-burned corneas of 30 New Zealand albino rabbits were categorized into three groups: AV treatment group that received AV gel-derived eye drops four times a day; medical therapy (MT) group that received conventional treatment; and the control group. Clinical examinations together with digital imaging of the corneas were performed on days 0, 1, 2, 4, and 7.

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Purpose: To report the clinical, microbiologic, confocal scan and histopathologic features of Aspergillus flavus keratitis which developed immediately after deep anterior lamellar keratoplasty (DALK).

Case Report: A 28-year-old woman underwent DALK using the big-bubble technique for keratoconus. The operation was uneventful, yielding a bare Descemet's membrane (DM) followed by transplantation of a corneal graft devoid of DM and endothelium.

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Purpose: To investigate the incidence, mechanisms, characteristics, and visual outcomes of traumatic wound dehiscence following keratoplasty.

Methods: Medical records of 32 consecutive patients with traumatic globe rupture following keratoplasty who had been treated at our center from 2001 to 2009 were retrospectively reviewed.

Results: The study population consisted of 32 eyes of 32 patients including 25 men and 7 women with history of corneal transplantation who had sustained eye trauma leading to globe rupture.

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Purpose: To report endothelial corneal graft rejection after administration of topical latanoprost eye drops.

Case Report: Two eyes of two patients with a history of multiple intraocular procedures prior to penetrating keratoplasty developed endothelial graft rejection one month after administration of topical latanoprost. Cystoid macular edema developed simultaneously in one patient.

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Purpose: To evaluate short-term changes in central corneal endothelial cell density and morphology after photorefractive keratectomy (PRK) with mitomycin-C (MMC) 0.02% in patients with moderate myopia.

Methods: In this prospective interventional case series, patients with moderate myopia (spherical equivalent refractive error from -4.

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Purpose: To compare spherical aberration and contrast sensitivity function following implantation of four different foldable posterior chamber intraocular lenses (IOLs), namely Sensar, Akreos AO, Tecnis, and AcrySof IQ.

Methods: In this randomized clinical trial, 68 eyes of 68 patients with senile cataracts underwent phacoemulsification and IOL implantation with Sensar (n=17), Akreos AO (n=17), Tecnis (n=17), or AcrySof IQ (n=17). Uncorrected visual acuity (UCVA) and best spectacle-corrected visual acuity (BSCVA), spherical aberration and contrast sensitivity function (CSF) were compared among the study groups, 3 months after surgery.

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Purpose: To evaluate in vivo confocal microscopic features of the cornea in chronic and delayed mustard gas keratopathy (MGK).

Design: Comparative cross-sectional study.

Participants And Controls: Twenty-two eyes of 22 consecutive patients with MGK and 28 eyes of 28 normal unoperated subjects were enrolled.

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Purpose: To report the outcomes of penetrating keratoplasty (PKP) in patients with macular corneal dystrophy (MCD).

Methods: This retrospective case series includes consecutive patients with MCD who underwent PKP from 1986 to 2006 with at least 6 months' follow-up. Main outcome measures included best spectacle-corrected visual acuity (BSCVA), postoperative astigmatism and graft survival.

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Purpose: To compare the visual outcomes and complications of lensectomy and posterior chamber intraocular lens (PCIOL) implantation with or without posterior capsulotomy and anterior vitrectomy in older subjects with pediatric cataracts.

Methods: Seventeen eyes of 12 children aged 10 to 15 years with congenital or developmental cataracts were randomly divided to two groups. Lensectomy and PCIOL (Alcon Acrysof MA60 AC) implantation was performed with (8 eyes) or without (9 eyes) posterior capsulotomy and anterior vitrectomy.

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Purpose: TO COMPARE SPHERICAL ABERRATION AND CONTRAST SENSITIVITY WITH TWO DIFFERENT TYPES OF ASPHERIC POSTERIOR CHAMBER INTRAOCULAR LENSES (PCIOLS): Tecnis Z9000 versus Akreos AO.

Methods: Thirty-four eyes of 34 patients undergoing phacoemulsification for senile cataracts were randomly assigned to implantation of Tecnis Z9000 or Akreos AO PCIOLs. Outcome measures included best-corrected visual acuity (BCVA), spherical aberration (SA) with 4 and 6 mm pupil diameters and contrast sensitivity under photopic and mesopic conditions at spatial frequencies of 1, 2, 5, 10 and 20 cycles per degree (cpd) three months postoperatively.

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Purpose: To report clinical manifestations and the bacteriologic profiles of three patients with bilateral bacterial keratitis following photorefractive keratectomy (PRK).

Methods: Photorefractive keratectomy was performed for mild to moderate myopia or compound myopic astigmatism. Bandage contact lenses were fitted at the conclusion of each surgery.

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Purpose: To evaluate the visual outcomes and complications of phacoemulsification (PE) and posterior chamber intraocular lens implantation, (PC IOL) in patients with Fuchs heterochromic iridocyclitis (FHIC).

Setting: Private clinic and an academic hospital.

Methods: In this noncomparative interventional case series, existing data for 41 eyes of 40 consecutive patients clinically diagnosed with FHIC and cataract were studied retrospectively.

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Purpose: To report the clinical features of 93 eyes of 48 patients with chronic and delayed-onset mustard gas keratitis. Clinicopathologic correlation in 5 eyes and a review of related literature are presented.

Design: Retrospective, noncomparative case series.

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Objective: To report the concomitant presentation of keratoconus and macular corneal dystrophy in two cases.

Methods: Two siblings with concomitant keratoconus and macular corneal dystrophy are presented. Complete ophthalmologic examination and computerized videokeratography were performed in both patients.

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