Publications by authors named "Mohammad-Reza Hajian"
Methodological biases are common in observational studies evaluating treatment effectiveness. The objective of this study is to emulate a target trial in a competing risks setting using hospital-based observational data. We extend established methodology accounting for immortal time bias and time-fixed confounding biases to a setting where no survival information beyond hospital discharge is available: a condition common to coronavirus disease 2019 (COVID-19) research data.
View Article and Find Full Text PDFObjective: To define the prevalence of hypothyroidism in women with chronic lower urinary tract symptoms (LUTS) and to compare the severity of each symptom between patients with hypothyroidism and controls.
Subjects And Methods: In this prospective observational study, we screened all adult women who came to the urology clinic between March 2017 and September 2020, and enrolled patients with chronic LUTS in the study. We assessed thyroid function.
Article Synopsis
- * Key findings indicated that longer hospital stays, pre-existing chronic conditions, high pulse rates, and abnormal laboratory results significantly increased mortality risks.
- * Specific lab indicators, like high neutrophil/lymphocyte ratios and elevated creatinine and potassium levels, were identified as strong independent predictors of in-hospital death from COVID-19.
Article Synopsis
- The coronavirus outbreak led to a high demand for intensive care, with a 49% mortality rate among critically ill patients primarily due to "cytokine storms."
- A study involving 37 patients with COVID-19 looked at the effects of hemoperfusion, a treatment aimed at addressing these respiratory failures, by comparing outcomes among those who received it with and without mechanical ventilation.
- The results indicated that while hemoperfusion improved certain health metrics, it did not significantly affect hospital or ICU stay duration, suggesting it might help reduce the need for mechanical ventilation if administered early in the disease.
Background: Renal ischemia-reperfusion (IR) injury has numerous deleterious effects on the kidney function. An experimental investigation was conducted to determine the possible protective role of testosterone (TES) and zinc (Zn) supplementations on the kidney function after IR injury in orchiectomized rats.
Methods: Orchiectomized rats ( = 32) were divided into the five groups as sham operated (Group 1), IR (Group 2), IR pretreatment with TES (IR + TES, Group 3), Zn (IR + Zn, Group 4), and TES + Zn (IR + TES + Zn, Group 5).