Effect of matrix metalloproteinase inhibitors on microtensile bond strength of dental composite restorations to dentin in use of an etch-and-rinse adhesive system.

Aim: This study assesses the effect of matrix metalloproteinases on microtensile bond strength (μTBS) of an etch-and-rinse adhesive system.

Methods: This in vitro study evaluated 88 extracted premolars. The teeth were sectioned to expose dentin and were then randomly divided into four groups (n = 22).