New lethal coronavirus disease 2019 (COVID-19), currently, has been converted to a disastrous pandemic worldwide. As there has been found no definitive treatment for the infection in this review we focused on molecular aspects of coenzyme Q (CoQ) and possible therapeutic potencies of CoQ against COVID-19 and similar infections. This is a narrative review in which we used some authentic resources including PubMed, ISI, Scopus, Science Direct, Cochrane, and some preprint databases, the molecular aspects of CoQ effects, regarding to the COVID-19 pathogenesis, have been analyzed and discussed.
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