Attenuation of isoprenaline-induced myocardial infarction by Rheum turkestanicum.

Background: Oxidative stress plays a major role in the pathogenesis of myocardial infarction. This study evaluated the cardioprotective effects of the hydroalcoholic extract of Rheum turkestanicum on isoprenaline-induced myocardial infarction (MI) in Wistar rats.

Methods: In this study, we used liquid chromatography-mass spectrometry to determine the active compounds present in the extract.

The possible mechanism of on pentobarbital-induced sleep in mice.

Background: Insomnia leads to the development of mental problems and missing of accuracy in affected persons. Various investigations have previously revealed which medicinal plants play a role in the improvement of insomnia. In this study, we evaluated the effect of hydro-alcoholic extract of on insomnia in mice.

Neuroprotective effects of in a mouse model of pentylenetetrazole-induced seizures.

Objective: Oxidative stress has pernicious effects on the brain. has antioxidant properties. We explored neuroprotective effect of against pentylenetetrazole (PTZ)-induced seizures.

Induction of cytotoxicity and apoptosis in FLT3 mutant expressing cells using novel pyrimido cyanoacrylates and quinoline derivatives.

Background: Aberrant activation of FMS-like tyrosine kinase 3 (FLT3) is associated with acute myeloid leukemia (AML). Leukemic cells expressing constitutively active FLT3 mutants are resistance to the current cancer therapies (radiotherapy and chemotherapy); hence, there is an increased interest to identify new agents for the treatment of AML. The main aim of this study was evaluating cytotoxic effects of novel pyrimidocyanoacrylates and quinoline derivatives on FLT3 overexpressing cells.

Hypnotic Effect of Red Cabbage () on Pentobarbital-Induced Sleep in Mice.

Objective: The present study was performed to investigate the effect of hydroalcoholic extract of red cabbage and its fractions on sleeping behavior in mice.

Materials And Methods: The extract and its fractions were injected to mice and sleep duration as well as sleep latency were recorded. Furthermore, toxicity of the extract was determined both and .