A simple predictable triple protocol for the management of double-curved canals (Case report of three cases).

Double-curved canals, despite their rarity, pose a great challenge to complete endodontic treatment, and the difficulty lies in negotiating these canals and reaching their apex, whereas the greatest difficulty lies in their shaping, disinfection, and obturation. Conventional methods require excessive preflaring to the level of the first curvature to facilitate access and handling of the second one. Modern technologies facilitate dealing with these cases without compromising the dental tissues, metal alloys have become more flexible, and activation techniques have made it possible to deliver irrigants deeper.

Comparative Evaluation of Potential Dentinal Microcracks Related to Instrumentation alongside Bypassed Broken Instruments: An Study.

Aim And Objective: To investigate the occurrence of microcracks in the canals containing broken instruments in the middle and apical thirds after instrumentation with various systems.

Materials And Methods: One-hundred and fifty mature mandibular premolars with single straight canal were collected and stored in distilled water. Samples were checked out from any preexisting deformation or cracks, and then standardized in length.

Ki-67 Prognostic Value in Different Histological Grades of Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma.

Introduction: Abnormal cell proliferation appears to be a possible predictor of tumorigenesis, Ki-67 protein expression is closely related to the cell proliferation and could be used as a biomarker for the growth in the most of human tumors. The aim of the study: Investigating of Ki-67 expression in the pathological grades of oral epithelial dysplasia and oral squamous cell carcinomas. Materials and Methods: The sample consisted of 30 formalin-fixed, paraffin-embedded specimens of oral epithelial dysplasia (OED), 30 other of oral squamous cell carcinomas (OSCC), and 10 normal oral epithelium (NOE) were conventionally stained with hematoxylin and eosin and immunohistochemically stained with Ki-67 monoclonal antibody.

Amelogenin is a Potential Biomarker for the Aggressiveness in Odontogenic Tumors.

Amelogenin (AMEL), the major structural protein of the enamel organic matrix, constitutes more than 90% of the enamel’s protein content, Aberrations of amelogenin are thought to be involved in the oncogenesis of odontogenic epithelium. The expression of amelogenin is possibly an indicator of differentiation of epithelial cells in the odontogenic tumors. Aim of the study: Investigating the expression of amelogenin in some odontogenic tumors, using an anti-amelogenin polyclonal antibody, and then compare it with AMEL expression in tooth buds as control.