In this work, the quasi-3D hyperbolic shear deformation theory (quasi-3D HSDT) is utilized to examine the dynamics of thick rectangular plates reinforced with rectangular nanofillers known as graphene nanoplatelets (GNPs). Agglomeration of the GNPs is incorporated and the mechanical characteristics like shear, elastic, and bulk moduli, Poisson's ratio, and density are analysed according to the mixture along with the Eshelby-Mori-Tanaka approach. Hamilton's principle is hired to derive the solving equations, the Navier approach is hired to present an analytical solution in the spatial domain, and the Newmark method is hired to provide an approximate solution in the time domain.
View Article and Find Full Text PDFMoringa oleifera plant grows in many countries worldwide and being utilized as a customary medication. The current study aimed to investigate the biological effect of Moringa oleifera leaf extract (MOE) alone or in combination with silver nanoparticles (AgNPs) on colon cancer, microbial cell growth. MOE was utilized in the green synthesis of AgNPs.
View Article and Find Full Text PDFBreast cancer is a heterogeneous disease and is the most common and prevalent form of malignancy diagnosed in women. lncRNAs are found to be frequently dysregulated in cancer, and its expression plays a critical role in tumorigenesis. The study included 100 histopathologically confirmed, newly diagnosed untreated patients of invasive ductal carcinoma (IDC) of breast cancer patients and 100 healthy subjects.
View Article and Find Full Text PDFIntroduction: COVID-19 was declared a pandemic in March 2020 by the World Health Organization. Control of COVID-19 depends on the potential vaccine and its successful delivery to a large portion of the population to develop herd immunity. All the governments have made a robust plan to distribute the vaccine to their people, but many countries could not achieve adequate vaccination coverage.
View Article and Find Full Text PDFBreast cancer is a heterogeneous disease in which genetic factors are involved in disease worsening and higher mortality. Epidemiological and clinical research revealed that breast cancer incidence continues to rise. 100 histopathologically confirmed untreated newly diagnosed cases of invasive ductal carcinoma (IDC) of breast and 100 healthy subjects were involved and blood samples were collected in non-EDTA plain vials.
View Article and Find Full Text PDFBackground: Type 2 diabetes mellitus [T2DM] has been one of the common diseases and is characterized by increased blood glucose levels and suggested that cell-free non-coding RNAs and microRNAs (miRNAs) have been demonstrated to serve as important diagnostic/prognostic biomarkers in diabetes.
Materials/methods: The present study included clinically confirmed newly diagnosed 200 cases of T2DM and 200 healthy subjects, and all the parameters were taken care in diagnosis. Blood samples collected in plain vials were used for cell-free total RNA extraction and after that 100ng of total RNA was used to synthesize the cDNA for cell-free lncRNA H19, miRNA-29a, and miRNA-29b expression using quantitative real-time PCR method.
Background And Aim: The soft tick is distributed throughout Africa, including Egypt. It primarily attacks camels, cattle, donkeys, and cows; and rarely affects humans. This study evaluated the acaricidal efficacy of ethanolic extract (Turmeric) on the second nymphs of and then investigated the safety of this herb in rabbits.
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