Publications by authors named "Mohammad Valikhani"
Moyamoya disease is a very rare chronic cerebrovascular disease of unknown etiology characterized by recurrent ischemic or hemorrhagic strokes. Initially diagnosed in Japan and named after finding puff of smoke like collateral blood vessels around the occluded blood vessels of circle of Willis. With increase awareness this disease is now diagnosed more often.
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- Many military personnel are at risk of lung damage from exposure to the jet fuel JP-8, leading to a study that uses microarray analysis on rat lung tissue.
- The study found significant changes in gene expression: 56 genes were affected at a low dose, with 86% downregulated, while at a higher dose, 66 genes were impacted with 42% upregulated, including genes linked to detoxification and antioxidant responses.
- The results confirm a potential link between JP-8 exposure and gene expression changes that could inform understanding of pulmonary responses in humans exposed to JP-8.