Publications by authors named "Mohammad Uzzaman"

This study presents the development of a novel microfluidic device designed for non-invasive impedance spectroscopy assessment of mammalian embryos, with a focus on bovine embryos. The system is capable of gentle embryo manipulation using precisely controlled negative pressure. The microfluidic device includes adjustable electrodes for measuring electrical properties directly.

View Article and Find Full Text PDF

Hot environments can negatively impact worker health, well-being, and productivity, especially in industrial and outdoor settings. Personal cooling systems (PCS) provide a solution, but current systems have limitations in cooling capacity, size, mobility, and battery life. This study introduces METAVEST, a lightweight and energy-efficient PCS comprising a cooling unit and a biomimetic vest.

View Article and Find Full Text PDF

Background: Frontonasal dysplasia type-2(FND2), a rare phenotypically variable and heterogeneous developmental anomaly resulting from mutation of the ALX4 gene, is primarily characterized by malformation of the skull and facial skeleton. This study was designed to showcase a clinical, imaging, and genetic analysis of FND2 in a consanguineous family of Bangladeshi origin.

Methodology: Clinical imaging and whole genome sequencing of mother, father and patient was done by using Nextera DNA flex library preparation kit (Illumina, USA) using Novaseq 6000 next generation sequencer to find out ALX4 mutation which causes FND2 in patient.

View Article and Find Full Text PDF

In the present study, we report the complete genome of five Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) from Bangladesh harboring mutations at Spike protein (E484K, Q677H, D614G, A67V, Q52R, Y144del, H69del, V70del, F888L) assigned to the B.1.525 lineage (Variant of interest).

View Article and Find Full Text PDF

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of COVID -19, is constantly evolving, requiring continuous genomic surveillance. In this study, we used whole-genome sequencing to investigate the genetic epidemiology of SARS-CoV-2 in Bangladesh, with particular emphasis on identifying dominant variants and associated mutations. We used high-throughput next-generation sequencing (NGS) to obtain DNA sequences from COVID-19 patient samples and compared these sequences to the Wuhan SARS-CoV-2 reference genome using the Global Initiative for Sharing All Influenza Data (GISAID).

View Article and Find Full Text PDF

The impact of SARS-CoV-2 infection on the nasopharyngeal microbiome has not been well characterised. We sequenced genetic material extracted from nasopharyngeal swabs of SARS-CoV-2-positive individuals who were asymptomatic (n = 14), had mild (n = 64) or severe symptoms (n = 11), as well as from SARS-CoV-2-negative individuals who had never-been infected (n = 5) or had recovered from infection (n = 7). Using robust filters, we identified 1345 taxa with approximately 0.

View Article and Find Full Text PDF

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic which has brought a great challenge to public health. After the first emergence of novel coronavirus SARS-CoV-2 in the city of Wuhan, China, in December 2019. As of March 2020, SARS-CoV-2 was first reported in Bangladesh and since then the country has experienced a steady rise in infections, resulting in 13,355,191 cases and 29,024 deaths as of 27 February 2022.

View Article and Find Full Text PDF

The microbiota of the nasopharyngeal tract (NT) play a role in host immunity against respiratory infectious diseases. However, scant information is available on interactions of SARS-CoV-2 with the nasopharyngeal microbiome. This study characterizes the effects of SARS-CoV-2 infection on human nasopharyngeal microbiomes and their relevant metabolic functions.

View Article and Find Full Text PDF
Article Synopsis
  • The study presents the nearly complete genome sequence of the Delta variant (B.1.617.2) of SARS-CoV-2.
  • This variant is linked to higher rates of transmission among individuals.
  • It also shows capabilities for immune evasion, making it a significant concern in the fight against COVID-19.
View Article and Find Full Text PDF
Article Synopsis
  • The study presents the complete genome sequence of the SARS-CoV-2 P.1 variant (20J/501Y.V3) from a female patient in Bangladesh diagnosed with COVID-19.
  • It includes detailed variant identifications and a phylogenetic analysis of the virus.
  • The patient had no recent travel history, indicating possible local transmission of the virus variant.
View Article and Find Full Text PDF

We report the sequencing of three severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes from Bangladesh. We have identified a unique mutation (NSP2_V480I) in one of the sequenced genomes (isolate hCoV-19/Bangladesh/BCSIR-NILMRC-006/2020) compared to the sequences available in the Global Initiative on Sharing All Influenza Data (GISAID) database. The data from this analysis will contribute to advancing our understanding of the epidemiology of SARS-CoV-2 in Bangladesh as well as worldwide at the molecular level and will identify potential new targets for interventions.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionqp4dnp6n525s1ndcu5lqpck1le749uj5): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once