Significant Association Between Genetic Polymorphism of Insulin-Like Growth Factor-2 mRNA Binding Protein-2 and Type 2 Diabetes Mellitus: A Population-Based Case-Control Study.

Objectives: To determine the association between IGF2BP2 polymorphisms and type 2 diabetes mellitus.

Methods: This study involved 422 individuals, 214 diabetes mellitus cases, and 208 healthy controls. The PCR-RFLP technique was used to determine the genotype of the IGF2BP2 gene for the SNPs rs4402960 (G>T) and rs1470579 (A>C).

Overexpression of rice High-affinity Potassium Transporter gene OsHKT1;5 improves salinity and drought tolerance in Arabidopsis.

Background: Rice is subjected to various environmental stresses, resulting in significant production losses. Abiotic stresses, particularly drought and salinity, are the leading causes of plant damage worldwide. The High-affinity Potassium Transporter (HKT) gene family plays an important role in enhancing crop stress tolerance by regulating physiological and enzymatic functions.

Identification of Novel Genomic Variants in COVID-19 Patients Using Whole-Exome Sequencing: Exploring the Plausible Targets of Functional Genomics.

Covid-19 caused by SARS-CoV-2 virus has emerged as an immense burden and an unparalleled global health challenge in recorded human history. The clinical characteristics and risk factors of COVID-19 exhibit considerable variability, leading to a spectrum of clinical severity. Moreover, the likelihood of exposure to the virus may differ based on comorbidity status as comorbid illnesses have mechanisms that can considerably increase mortality by reducing the body's ability to withstand injury.

In-depth genomic characterisation of SARS-CoV-2 variants from Egypt exhibited heterogeneous lineages.

Background: Genetic variation of SARS-CoV-2 remains a public health challenge worldwide because of it influences the pathogenicity and transmissibility of the virus.

Aims: To determine the genomic mutations of SARS-CoV-2 isolated in Egypt.

Methods: This was an in silico cross-sectional study of 200 SARS-CoV-2 variants of concern, which were retrieved from the National Centre for Biotechnology Information on 11 January 2021 and aligned with the original Wuhan strain (NC_045512).

Distribution and disparities of healthy lifestyles and noncommunicable diseases risk factors between men and women aged 20-59 years in Bangladesh: Evidence from a nationwide survey.

Background: Noncommunicable diseases (NCDs) are public health threats globally and recognized impediments to socioeconomic development. This study aimed to identify the prevalence and clustering of NCDs risk factors among Bangladeshi men and women aged 20-59 years using nationally representative data.

Methods: This study was conducted in 82 rural, nonslum urban, and slum clusters across all eight administrative divisions of Bangladesh using multistage cluster sampling.

Meaning of Work Participation After Spinal Cord Injury in Bangladesh: A Qualitative Study in a Low- and Middle-Income Country Context.

Purpose: This study aimed to explore the meaning of work participation for people with spinal cord injury (SCI) in Bangladesh.

Methods: Narrative inquiry methodological framework was used to explore the meaning of work participation after SCI. Face-to-face interviews with twenty adults with SCI, who were either living in the community or in-patients at a rehabilitation center.

Potential association between allergenic food exposure and skin disease in Bangladesh: An application of principal component logistic regression (PCLR).

Background And Aim: Allergenic foods can trigger skin conditions, yet their impact in Bangladesh remains underexplored. This study aims to investigate the potential association between exposure to allergenic foods and the development of skin disease across Bangladesh.

Methods: We conducted a cross-sectional survey with 970 respondents from the divisions of Dhaka, Sylhet, Rangpur, and Chattogram who self-reported skin disease triggered by food allergens.

Preparation of a chiral hyperbranched polymer based on cinchona alkaloids and investigation of its catalytic activity in asymmetric reactions.

Cinchona alkaloid-derived sulfonamides and ester dimers containing chiral hyperbranched polymers have been successfully synthesized and applied as catalysts in asymmetric reactions. Several hyperbranched polymers derived from cinchona alkaloids, incorporating sulfonamides and esters, were synthesized through Mizoroki-Heck coupling polymerization. These polymers were subsequently applied in enantioselective Michael addition reactions.

Computer-aided discovery of novel SmDHODH inhibitors for schistosomiasis therapy: Ligand-based drug design, molecular docking, molecular dynamic simulations, drug-likeness, and ADMET studies.

Schistosomiasis, also known as bilharzia or snail fever, is a tropical parasitic disease resulting from flatworms of the Schistosoma genus. This often overlooked disease has significant impacts in affected regions, causing enduring morbidity, hindering child development, reducing productivity, and creating economic burdens. Praziquantel (PZQ) is currently the only treatment option for schistosomiasis.

CNN-based deep learning approach for classification of invasive ductal and metastasis types of breast carcinoma.

Objective: Breast cancer is one of the leading cancer causes among women worldwide. It can be classified as invasive ductal carcinoma (IDC) or metastatic cancer. Early detection of breast cancer is challenging due to the lack of early warning signs.

Perceptions and attitudes of nurse practitioners toward artificial intelligence adoption in health care.

Background: With the ever-increasing integration of artificial intelligence (AI) into health care, it becomes imperative to gain an in-depth understanding of how health care professionals, specifically nurse practitioners, perceive and approach this transformative technology.

Objectives: This study aimed to gain insights into nurse practitioners' perceptions and attitudes toward AI adoption in health care.

Methods: This qualitative research employed a descriptive and phenomenological approach using in-depth interviews.

Whole-Exome Sequencing Detecting a Recurrent Pathogenic Mutation, p.His63Asp (H63D) in COVID-19 Patients and Its Effect on Mortality.

Background: In recent years, various coronaviruses have caused severe respiratory illnesses worldwide. For example the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections of COVID-19 outbreak in 2019 in Wuhan, China. Genome-wide association studies (GWAS) have significantly expanded our comprehension of how specific genetic variations are linked to diseases.

Bifurcation, chaos, and stability analysis to the second fractional WBBM model.

This manuscript investigates bifurcation, chaos, and stability analysis for a significant model in the research of shallow water waves, known as the second 3D fractional Wazwaz-Benjamin-Bona-Mahony (WBBM) model. The dynamical system for the above-mentioned nonlinear structure is obtained by employing the Galilean transformation to fulfill the research objectives. Subsequent analysis includes planar dynamic systems techniques to investigate bifurcations, chaos, and sensitivities within the model.

Unhealthy Food and Sugar-Sweetened Beverage Consumption Among Bangladeshi Elderly People and Their Sociodemographic Determinants: Findings From a Nationally Representative Cross-Sectional Study.

Background: Savory crispy or fried snack (SCFS), sugary snack (SS), and sugar-sweetened beverage (SSB) consumption are associated with a higher prevalence of obesity and non-communicable diseases. So, we estimated the consumption of SCFS, SS, and SSB among elderly males and females in Bangladesh. We also reported the factors associated with their consumption using data from a nationwide cross-sectional study.

An innovative fractional-order evolutionary game theoretical study of personal protection, quarantine, and isolation policies for combating epidemic diseases.

This study uses imposed control techniques and vaccination game theory to study disease dynamics with transitory or diminishing immunity. Our model uses the ABC fractional-order derivative mechanism to show the effect of non-pharmaceutical interventions such as personal protection or awareness, quarantine, and isolation to simulate the essential control strategies against an infectious disease spread in an infinite and uniformly distributed population. A comprehensive evolutionary game theory study quantified the significant influence of people's vaccination choices, with government forces participating in vaccination programs to improve obligatory control measures to reduce epidemic spread.

Bifurcation analysis and new waveforms to the first fractional WBBM equation.

This research focuses on bifurcation analysis and new waveforms for the first fractional 3D Wazwaz-Benjamin-Bona-Mahony (WBBM) structure, which arises in shallow water waves. The linear stability technique is also employed to assess the stability of the mentioned model. The suggested equation's dynamical system is obtained by applying the Galilean transformation to achieve our goal.

The long-term effects of childhood circumstances on older individuals: A systematic review.

Childhood experiences are known to shape individuals' development and can influence various aspects of life later on. Understanding the long-term effects is crucial for informing interventions and policies aimed at promoting healthy aging. This review aimed to explore the long-term effects of childhood experiences on older individuals.

Bangla_MER: A unique dataset for Bangla mathematical entity recognition.

Mathematical entity recognition is essential for machines to define and illustrate mathematical substance faultlessly and to facilitate sufficient mathematical operations and reasoning. As mathematical entity recognition in the Bangla language is novel, to our best knowledge, there is no available dataset exists in any repository. In this paper, we present state of the art Bangla mathematical entity dataset containing 13,717 observations.

Socio-economic status and pregnancy complications and their impact on antenatal care services provided at home and Upazila health complex.

The stage of pregnancy is crucial for women of reproductive age and their families. However, in low- and middle-income countries like Bangladesh, antenatal and postnatal care are not widely practiced due to various socio-economic factors, such as low education levels, income, age, pregnancy knowledge, and limited healthcare facilities. The objective of this study was to examine the factors associated with antenatal care in two locations in Bangladesh based on the data collected from the Bangladesh Demographic and Health Survey (BDHS) 2017-2018.

Behavioral game of quarantine during the monkeypox epidemic: Analysis of deterministic and fractional order approach.

This work concerns the epidemiology of infectious diseases like monkeypox (mpox) in humans and animals. Our models examine transmission scenarios, including transmission dynamics between humans, animals, and both. We approach this using evolutionary game theory, specifically the intervention game-theoretical (IGT) framework, to study how human behavior can mitigate disease transmission without perfect vaccines and treatments.

Understanding the relationship between stay-at-home measures and vaccine shortages: a conventional, heterogeneous, and fractional dynamic approach.

In light of the global prevalence of a highly contagious respiratory disease, this study presents a novel approach to address the pressing and unanticipated issues by introducing a modified vaccination and lockdown-centered epidemic model. The rapid spread of the disease is attributed to viral transmissibility, the emergence of new strains (variants), lack of immunization, and human unawareness. This study aims to provide policymakers with crucial insights for making informed decisions regarding lockdown strategies, vaccine availability, and other control measures.

A non-singular fractional-order logistic growth model with multi-scaling effects to analyze and forecast population growth in Bangladesh.

This paper is primarily concerned with data analysis employing the nonlinear least squares curve fitting method and the mathematical prediction of future population growth in Bangladesh. Available actual and adjusted census data (1974-2022) of the Bangladesh population were applied in the well-known autonomous logistic population growth model and found that all data sets of the logistic (exact), Atangana-Baleanu-Caputo (ABC) fractional-order derivative approach, and logistic multi-scaling approximation fit with good agreement. Again, the existence and uniqueness of the solution for fractional-order and Hyers-Ulam stability have been studied.

Analyzing the Costs and Benefits of Utilizing a Mixed-Strategy Approach in Infectious Disease Control under a Voluntary Vaccination Policy.

Infectious diseases pose significant public health risks, necessitating effective control strategies. One such strategy is implementing a voluntary vaccination policy, which grants individuals the autonomy to make their own decisions regarding vaccination. However, exploring different approaches to optimize disease control outcomes is imperative, and involves assessing their associated costs and benefits.

New wave behaviors of the Fokas-Lenells model using three integration techniques.

In this investigation, we apply the improved Kudryashov, the novel Kudryashov, and the unified methods to demonstrate new wave behaviors of the Fokas-Lenells nonlinear waveform arising in birefringent fibers. Through the application of these techniques, we obtain numerous previously unreported novel dynamic optical soliton solutions in mixed hyperbolic, trigonometric, and rational forms of the governing model. These solutions encompass periodic waves with W-shaped profiles, gradually increasing amplitudes, rapidly increasing amplitudes, double-periodic waves, and breather waves with symmetrical or asymmetrical amplitudes.