Publications by authors named "Mohammad Tobeiha"

Pituitary adenoma (PA) is the third most common primary intracranial tumor in terms of overall disease incidence. Although they are benign tumors, they can have a variety of clinical symptoms, but are mostly asymptomatic, which often leads to diagnosis at an advanced stage when surgical intervention is ineffective. Earlier identification of PA could reduce morbidity and allow better clinical management of the affected patients.

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Systemic lupus erythematosus (SLE), as an immunological illness, frequently impacts young females. Both vulnerabilities to SLE and the course of the illness's clinical symptoms have been demonstrated to be affected by individual differences in non-coding RNA expression. Many non-coding RNAs (ncRNAs) are out of whack in patients with SLE.

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Bone remodels via resorption and formation, two phenomena that continuously occur in bone turnover. The RANKL/RANK/OPG pathway is one of the several mechanisms that affect bone turnover. The RANKL/OPG ratio has a substantial role in bone resorption.

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The pineal gland is a neuroendocrine gland which produces melatonin, a neuroendocrine hormone with critical physiological roles in the circadian rhythm and sleep-wake cycle. Melatonin has been shown to possess anti-oxidant activity and neuroprotective properties. Numerous studies have shown that melatonin has significant functions in cardiovascular disease, and may have anti-aging properties.

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Article Synopsis
  • Many cellular signaling pathways play a crucial role in regulating important processes such as cell growth, movement, and programmed cell death, and their disruption can lead to cancer development and progression.
  • Recent research has highlighted the potential of natural products, like quercetin—a flavonol found in everyday foods—as effective agents in cancer treatment due to their ability to inhibit tumor growth through various mechanisms.
  • This summary focuses on the therapeutic benefits of quercetin specifically in gastrointestinal cancers, including pancreatic, gastric, colorectal, esophageal, hepatocellular, and oral cancers.
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Article Synopsis
  • * Recent research is exploring natural compounds that can combat cancer in two ways: by directly targeting cancer cells and by influencing cancer cell signaling pathways.
  • * Some natural plant-derived agents can enhance the effectiveness of traditional chemotherapy and help reduce its side effects, making them an important focus in osteosarcoma treatment.
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Bones as an alive organ consist of about 70% mineral and 30% organic component. About 200 million people are suffering from osteopenia and osteoporosis around the world. There are multiple ways of protecting bone from endogenous and exogenous risk factors.

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