Translation, Cross-Cultural Adaptation, Reliability, and Validity of the Persian Version of the Neck Outcome Score Questionnaire in Iranian Patients With Nonspecific Neck Pain.

Objective: The primary purpose of this study was to translate and culturally adapt the neck outcome score (NOOS) questionnaire into Persian language and investigate its reliability and validity.

Methods: The NOOS questionnaire was translated into Persian language and culturally adapted according to American Academy of Orthopaedic Surgeons guidelines. One hundred four patients with nonspecific neck pain were requested to complete the Persian version of the NOOS questionnaire, 36-item short form survey (SF-36), and neck disability index (NDI) questionnaire.

E22G Aβ40 fibril structure and kinetics illuminate how Aβ40 rather than Aβ42 triggers familial Alzheimer's.

Arctic (E22G) mutation in amyloid-β (Aβ enhances Aβ40 fibril accumulation in Alzheimer's disease (AD). Unlike sporadic AD, familial AD (FAD) patients with the mutation exhibit more Aβ40 in the plaque core. However, structural details of E22G Aβ40 fibrils remain elusive, hindering therapeutic progress.

The association of osteoporosis and cardiovascular disease risk score based on the Framingham and ACC/AHA risk prediction models: a cross-sectional analysis of Bushehr Elderly Health Program.

Background: The association between osteoporosis and cardiovascular disease, two major health problems, has been reported in some studies. In this study was aimed to investigate the relationship between osteoporosis and the CVD risk score based on Framingham and American College of Cardiology and the American Heart Association (ACC/AHA) prediction models in the population over 60 years old.

Methods: A cross-sectional analysis was conducted on data from 2389 men and women participating in the Bushehr Elderly Health (BEH) program.

Comparative effect of triamcinolone/lidocaine ultrasonophoresis and injection on pain, disability, quality of life in patients with acute rotator cuff related shoulder pain: a double blinded randomized controlled trial.

Background: Alleviating inflammation should be considered as one of the first steps of the treatment plan in patients with acute rotator cuff related shoulder pain (RCRSP).

Objective: To compare the effects of triamcinolone/lidocaine ultrasonophoresis, injection on pain, disability, and quality of life in patients with acute RCRSP.

Methods: A total of 28 acute RCRSP patients were randomly allocated into two groups of ultrasonophoresis and injection.

The Responsiveness of Three Persian Outcome Measures Following Physiotherapy Intervention in Patients with Chronic Non-Specific Neck Pain.

Objectives: A prospective cohort study to evaluate and compare the responsiveness of the Persian version of the neck disability index (NDI), neck pain & disability scale (NPDS), neck outcome score (NOOS), and to determine the minimal clinically important difference (MCID) and minimal detectable change (MDC). To date, no studies have made a direct comparison between the responsiveness of the Persian version of NPDS, NDI, and NOOS questionnaires.

Methods: At the end of the study, 55 patients with chronic non-specific neck pain completed the NPDS, NDI, and NOOS questionnaires at the beginning and end of three weeks of physiotherapy treatment.

Molecular Characteristics of Staphylococcus aureus Strains Isolated from Nasal Cavity and Wound Infections Among Diabetic Patients.

Staphylococcus aureus is the most common pathogen contributing to diabetic foot infections (DFI). Nasal transmission of S. aureus potentially increases the risk of endogenous infection.

Fabrication and implementation of bimetallic Fe/Zn nanoparticles (mole ratio 1:1) loading on hydroxyethylcellulose - Graphene oxide for removal of tetracycline antibiotic from aqueous solution.

Tetracycline (TC) as an antibiotic with high consumption causes the spread of contamination in an aqueous solution. In recent decades, antibiotics are the main cause of hindering the growth of microorganisms. Also, they are one of the important groups of pharmaceuticals with extensive usage in human and veterinary medicine.

The effect of behavioral therapy based counseling with anxious mothers on their infants' colic: a randomized controlled clinical trial.

Background: Given the possible effect of maternal anxiety on the severity of colic pain in infants, this study aimed to investigate the effects of behavioral therapy counseling on infantile colic (primary outcome), maternal anxiety, and mother-infant attachment (secondary outcomes) in anxious mothers with colicky infants.

Method: This randomized controlled clinical trial was conducted on 46 anxious mothers of 2-6-weeks-old exclusively breastfed colicky infants who had a score of 112 and above according to the Postpartum Specific Anxiety Scale (PSAS), reffered to the pediatric clinics of Al-Zahra, Taleghani and Children Hospitals of Tabriz, Iran. The participants were randomly assigned to the intervention (n = 23) and control (n = 23) groups using randomized block design.

Efficacy of low-level laser therapy on pain, disability, pressure pain threshold, and range of motion in patients with myofascial neck pain syndrome: a systematic review and meta-analysis of randomized controlled trials.

Low-level laser therapy (LLLT) is one of recent modalities for treatment of myofascial neck pain (MNP). Several RCTs have been conducted on its effectiveness. The aim of this comprehensive meta-analysis was to evaluate the effectiveness of LLLT on MNP.

Diabetic foot care course: a quasi-experimental study on E-learning versus interactive workshop.

Background: Nurses, as multidisciplinary Diabetic Foot Care (DFC) team members, need to be trained in DF prevention and management. Regarding the increasing use of e-learning educational courses as the new learning strategy with potential benefits among health care providers, this study attempted to evaluate the educational effects of an e-learning course on DFC compared to that of an interactive workshop in the related knowledge attainment.

Methods: This was a quasi-experimental study compared two non-randomized groups consisting of nurses who attended an e-learning course (intervention group) and a face-to-face interactive workshop (control group) on DFC using a pre- and post-test design.

Microfluidic platform for synthesis and optimization of chitosan-coated magnetic nanoparticles in cisplatin delivery.

In this study, magnetic core/chitosan shell Nanoparticles (NPs) containing cisplatin were synthesized via cisplatin complexation with tripolyphosphate as the chitosan crosslinker using two different procedures: a conventional batch flow method and a microfluidic approach. An integrated microfluidic device composed of three stages was developed to provide precise and highly controllable mixing. The comparison of the results revealed that NPs synthesized in microchannels were monodisperse 104 ± 14.

Validation of an Analytical Method for Simultaneous Determination of 18 Persistent Organic Pollutants in Trout Using LLE Extraction and GC-MS/MS.

Persistent organic pollutants, (POPs), are vast distributed compounds in environment which are recognized as one of the global pollution problems. These groups of materials being dangerous due to their high stability are accumulated in animal tissues and occurring in the food chain. One of the major paths through which persistent organic combinations access to human body is consuming polluted foods, particularly, fishes.

Rolling adhesion of leukocytes on soft substrates: Does substrate stiffness matter?

Cell rolling on vascular endothelium under hydrodynamic blood flow is critical for realization of many physiological and pathological processes, such as inflammatory response and tumor metastasis. The blood-borne cells are in direct contact with the inner layer of endothelium, formed by a highly compliant layer of endothelial cells. The effect of endothelial stiffness on the adhesion and motion of rolling cells is poorly understood.

Phosphate-solubilizing bacteria and silicon synergistically augment phosphorus (P) uptake by wheat (Triticum aestivum L.) plant fertilized with soluble or insoluble P source.

Phosphorus (P) deficiency is one of the major problems in agricultural soils for crop production around the world. Use of silicon (Si) and phosphate-solubilizing bacteria (PSB) is known as one of the most effective and economical ways for increasing P availability and improving P use efficiency under low P conditions. However, little is known about the alleviative role of Si and PSB together in mitigating P-deficiency stress and in improving P use efficiency in Triticum aestivum L.

On Stability of Specific Adhesion of Particles to Membranes in Simple Shear Flow.

Adhesion of carrier particles to the luminal surface of endothelium under hemodynamic flow conditions is critical for successful vascular drug delivery. Endothelial cells (ECs) line the inner surface of blood vessels. The effect of mechanical behavior of this compliant surface on the adhesion of blood-borne particles is unknown.

Comparison between Different Extraction Methods for Determination of Primary Aromatic Amines in Food Simulant.

The primary aromatic amines (PAAs) are food contaminants which may exist in packaged food. Polyurethane (PU) adhesives which are used in flexible packaging are the main source of PAAs. It is the unreacted diisocyanates which in fact migrate to foodstuff and then hydrolyze to PAAs.

Polydispersity controls the strength of semi-flexible polymer networks.

The classical theory of polymer elasticity is built upon the assumption of network monodispersity-the premise that polymer networks are comprised of sub-chains of equal length. The crosslinking of biopolymers, however, is a random process and the resultant networks are likely to be polydisperse. The effect of structural polydispersity on the mechanical behavior of biopolymer networks is not well understood.

Facile preparation of multifunctional carbon nanotube/magnetite/polyaniline nanocomposite offering a strong option for efficient solid-phase microextraction coupled with GC-MS for the analysis of phenolic compounds.

The aim of this study was to synthesize a highly efficient organic-inorganic nanocomposite. In this research, the carbon nanotube/magnetite/polyaniline nanocomposite was successfully prepared through a facile route. Monodisperse magnetite nanospheres were prepared through the coprecipitation route, and polyaniline nanolayer as a modified shell with a high surface area was synthesized by an in situ growth route and characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, X-ray diffraction, and energy-dispersive X-ray spectroscopy.

The toxicity study of synthesized inverse carnosine peptide analogues on HepG2 and HT-29 cells.

Objective: Cancer has risen as the main cause of diseases with the highest rate of mortality in the world. Drugs used in cancer, usually demonstrate side effects on normal tissues. On the other hand, anticancer small peptides, effective on target tissues, should be safe on healthy organs, as being naturally originated compounds.

Evidence for the involvement of the GABAergic, but not serotonergic transmission in the anxiolytic-like effect of bisabolol in the mouse elevated plus maze.

Bisabolol (α-(-)-bisabolol) is a sesquiterpene which is a part of the essential oil of a variety of plants, but its common source is German chamomile. Several bioactivities including anti-inflammatory, anti-nociceptive, and anti-tumor effects were attributed to bisabolol. However, the neuropharmacological properties of bisabolol have not yet been reported.

Force-driven growth of intercellular junctions.

Mechanical force regulates the formation and growth of cell-cell junctions. Cadherin is a prominent homotypic cell adhesion molecule that plays a crucial role in establishment of intercellular adhesion. It is known that the transmitted force through the cadherin-mediated junctions directly correlates with the growth and enlargement of the junctions.

Fe(3)O(4)/polyethylene glycol nanocomposite as a solid-phase microextraction fiber coating for the determination of some volatile organic compounds in water.

A high-performance metal oxide polymer magnetite/polyethylene glycol nanocomposite was prepared and coated in situ on the surface of the optical fiber by sol-gel technology. The magnetite nanoparticles as nanofillers were synthesized by a coprecipitation method and bonded with polyethylene glycol as a polymer. The chemically bonded coating was evaluated for the headspace solid-phase microextraction of some environmentally important volatile organic compounds from aqueous samples in combination with gas chromatography and mass spectrometry.

Point mutations in Escherichia coli DNA pol V that confer resistance to non-cognate DNA damage also alter protein-protein interactions.

Y-family DNA polymerases are important for conferring cellular resistance to DNA damaging agents in part due to their specialized ability to copy damaged DNA. The Escherichia coli Y-family DNA polymerases are encoded by the umuDC and dinB genes. UmuC and the cleaved form of UmuD, UmuD', form UmuD'2C (pol V), which is able to bypass UV photoproducts such as cyclobutane pyrimidine dimers and 6-4 thymine-thymine dimers, whereas DinB is specialized to copy N(2)-dG adducts, such as N(2)-furfuryl-dG.

In-situ Pb(2+) remediation using nano iron particles.

Originally, application of nano zero valent iron (nZVI) particles for the removal of lead (Pb(2+)) in porous media was studied. At first, stabilized nZVI (S-nZVI) was prepared and characterized, then used in batch and continuous systems. Based on the batch experiments, corresponding reaction kinetics well fitted with the pseudo-first-order adsorption model, and reaction rate ranged from 0.