Dystonia in Ataxia Telangiectasia: A Case Report with Novel Mutations.

Ataxia telangiectasia (A-T) is a common, genetically inherited cause of early childhood-onset ataxia that is classically characterized by progressive cerebellar malfunction, oculocutaneous telangiectasia, genome instability, and immunodeficiency. There is vast phenotype variation in patients with A-T and recently, dystonia, an extrapyramidal movement disorder. Here, we report the case of a 10-year-old girl who had experienced repeated diarrhea and mild gait ataxia since the age of two years.

Characterization of large array of plasmonic nanoparticles on layered substrate: dipole mode analysis integrated with complex image method.

In this paper, an efficient analytical method for characterizing large array of plasmonic nanoparticles located over planarly layered substrate is introduced. The model is called dipole mode complex image (DMCI) method since the main idea lies in modeling a subwavelength spherical nanoparticle at its electric scattering resonance with an induced electric dipole and representing the electromagnetic (EM) fields of this electric dipole over the layered substrate in terms of finite complex images. The major advantages of the proposed method are its accuracy and rapid calculation in characterizing various kinds of large periodic and aperiodic arrays of nanoparticles on layered substrates.