Cutaneous Metastasis From Prostate Cancer on Posttherapeutic 177 Lu-Prostate-Specific Membrane Antigen Scan.

In this note, we aim to present a patient with a known case of prostate cancer with widespread metastasis to the skeleton and liver who has undergone several cycles of chemoradiotherapy. The patient received 2 doses of 177 Lu-prostate-specific membrane antigen therapy, in which several zones of uptake were detected on the thoracic wall compatible with cutaneous metastatic lesions of prostate cancer.

The effects of Alpha-2a and Beta-1a Interferons on the Coronavirus disease 2019 prognosis.

Background: The pandemic coronavirus disease 2019 (COVID-19) has been associated with substantial mortality worldwide. Efforts have continued to find an effective treatment for COVID-19. In vitro activity of interferon (IFN) subtypes has been shown against the SARS-CoV and MERS-CoV.

Effectiveness of Fortified Garlic Extract Oral Capsules as Adjuvant Therapy in Hospitalized Patients with Coronavirus Disease 2019: A Triple-Blind Randomized Controlled Clinical Trial.

Background: Herbal medicines have been extensively used to treat coronavirus disease 2019 (COVID-19). Garlic, known to exert antiviral and anti-inflammatory effects, can be coadministered with standard treatments to combat COVID-19.

Objectives: The aim of the study was to evaluate the efficacy and safety profile of Gallecina oral capsules (Samisaz Pharmaceutical Company, Mashhad, Iran), a fortified garlic extract, as adjunctive therapy to improve the clinical status and symptoms in noncritically ill patients hospitalized for COVID-19.

The effect of royal jelly and silver nanoparticles on liver and kidney inflammation.

Objective: Royal jelly (RJ) is a honey bee product for which, anti-inflammatory properties were shown . Nanoparticles, including nano-silver (NS), are plausible inflammation inducers that act by activation of immune cells and consequent production of pro-inflammatory cytokines. This project aimed to explore immunomodulatory effects of royal jelly and nano-silver on the kidney and liver.

Emotionally valenced and modality-specific dual tasks: Effects on voluntary reminding and proactive interference in trauma-exposed individuals suffering from PTSD.

People suffering from posttraumatic stress disorder (PTSD) often experience distressing traumatic memories. Therapeutic methods that apply a secondary task while clients recall a trauma memory may further assist in modifying the vividness and emotionality of the trauma memory and in reducing intrusions. In this experiment, we aimed to investigate whether the emotional valence (positive vs.

Visceral leishmaniasis in an adult case in Northeast of Iran: A case report and literature review.

Leishmaniasis is a rare complication in adult cases even in endemic areas. Here, the first report of visceral leishmaniasis in a young woman in northeast of Iran has been described.

Proactive Interference in Posttraumatic Stress Disorder.

Deficits in working memory (WM) have a role in maintaining posttraumatic stress disorder (PTSD) symptoms, including intrusions, which are a hallmark of PTSD symptomatology. As intrusions are distressing and uncontrollable, it is important to investigate whether PTSD is associated with altered control of proactive interference in WM. Moreover, it is important to consider both verbal and visual WM, as previous research has demonstrated a visual versus verbal dissociation in PTSD.

The effects of fluoxetine on the human adipose-derived stem cell proliferation and differentiation.

Fluoxetine is one of the most commonly used antidepressants. Fluoxetine could prevent the mesenchymal stem cell differentiation in lung fetus of rat. Moreover, the mesenchymal stem cells are also present in adult tissues.

Transient brain hypothermia reduces the reperfusion injury of delayed tissue plasminogen activator and extends its therapeutic time window in a focal embolic stroke model.

It has been reported that restriction of reperfusion after thrombolytic therapy in ischemic stroke may reduce tissue plasminogen activator (tPA) adverse effects and extend its time window. We examined whether shortIt has been reported that restriction of reperfusion after thrombolytic therapy in ischemic stroke may reduce tissue plasminogen activator (tPA) adverse effects and extend its time window. We examined whether short-term and mild local brain cooling can prevent hyperemia and/or adverse effects of delayed tPA in rat embolic stroke model.

The expression of HoxB5 and SPC in neonatal rat lung after exposure to fluoxetine.

Objective: Approximately 10% of pregnant women suffer from pregnancy-associated depression. Fluoxetine, as a selective serotonin reuptake inhibitor, is being employed as a therapy for depressive disorders. The present study aimed to determine the effects of fluoxetine on neonatal lung development.

The Persian Version of a Participation Scale: Is It Valid and Reliable Enough for Use among Iranian Patients with Multiple Sclerosis?

Background And Purpose: The aim of this study was to determine the face and criterion validity, stability reliability, and internal consistency of the Persian version of the Impact on Participation and Autonomy (IPA-p) scale among Iranian people with multiple sclerosis (MS).

Methods: Trained experts interviewed 364 MS patients and their relatives to assess the criterion validity, stability reliability, and internal consistency of the IPA-p scale. Ten specialists from different disciplines were also recruited to assess its face validity.

The Effect of Loneliness on Social Networking Sites Use and Its Related Behaviors.

Introduction: The current research was conducted to examine the effect of "Loneliness", on time spent in Social Networking Sites (S.N.S), main reasons for S.

Effect of aqueous extract of Achillea millefolium on the development of experimental autoimmune encephalomyelitis in C57BL/6 mice.

Objective: Achillea millefolium (A. millefolium) is widely used as an anti-inflammatory remedy in traditional and herbal medicine. In this study, we investigated the effect of an aqueous extract from A.

Biochemical and hemato-immunological parameters in juvenile beluga (Huso huso) following the diet supplemented with nettle (Urtica dioica).

The present study investigated the effects of different dietary nettle (Urtica dioica) levels on biochemical, hematological and immunological parameters in beluga (Huso huso). Fish were divided into 4 groups before being fed for 8 weeks with 0%, 3%, 6% and 12% of nettle. The blood samples were collected on week 4 and 8.

Proinflammatory cytokines in the embolic model of cerebral ischemia in rat.

Increased levels of proinflammatory cytokines have been recorded after the onset of transient or permanent brain ischemia and are usually associated with exacerbation of ischemic injury. Embolic stroke model is more relevant to the pathophysiological situation in such patients, because the majority of ischemic injuries in humans are induced by old thrombi that originate from the heart and carotid arteries. Therefore, the aim of the present study was to investigate changes of inflammatory cytokines after embolic stroke.

Drug utilization evaluation of imipenem and intravenous ciprofloxacin in a teaching hospital.

Drug Utilization Evaluation (DUE) studies are designed to assess drug usage appropriateness. We aim to evaluate the drug utilization of intravenous ciprofloxacin and imipenem, two of the broad spectrum antibiotics that consume a significant proportion of our hospitals' outlay, in different wards of a teaching hospital in Zabol. During a 5 months period (December 2010 to May 2011), 263 patients who received imipenem or intravenous ciprofloxacin were assigned to this study.

Coexistence of multiple arterial variations in the genitourinary system.

Variations in the renal, adrenal and testicular arteries are of clinical significance as well as anatomical and embryological interest. The present case report describes the incidental finding of unilateral multiple renal arteries on the right side with bilateral variant testicular arteries, which had not been reported so far. These variations were observed during routine dissection of the abdominal region in an Iranian cadaver.

Lack of significance of the BRCA2 promoter methylation status in different genotypes of the MTHFR a1298c polymorphism in ovarian cancer cases in Iran.

Objective: Promoter methylation, which can be regulated by MTHFR activity, is associated with silencing of genes. In this study we evaluated the methylation status (type) of the BRCA2 promoter in ovarian cancer patients carrying different genotypes of the MTHFR gene (A or C polymorphisms at position 1298).

Methods: The methylation type of the BRCA2 promoter was evaluated using bisulfate-modified DNA in methylation- specific PCR and the MTHFRa1278c polymorphism was assessed by PCR-RFLP.

Effects of cognitive-behavioral group therapy on recurrent headaches in Iranian culture.

This study investigated effects of applying cognitive-behavioral group therapy on recurrent headaches. Among Shiraz University female students complaining of headaches, 20 patients, each reporting either migraine or tension-type headaches and who met the 1988 International Headache Society diagnosis criteria for migraine and tension-type headaches, formed two groups. Analysis showed cognitive-behavioral group therapy decreased headache index significantly.

Evaluation of effects of methamphetamine repeated dosing on proliferation and apoptosis of rat germ cells.

Methamphetamine (MAMP) is a central nervous system stimulant that is increasingly abused especially by teenagers and young adults, a group in its reproductive age. MAMP effects on the male reproductive system are not clear. In this experimental study, we evaluated the effects of MAMP administration on proliferation and apoptosis in seminiferous tubules of rat testis.

Factor structure of the Depression Self-Rating Scale in an Iranian adolescent sample.

Previous research showed concurrent validity for the Depression Self-rating Scale for Iranian adolescents, so the present purpose was to evaluate construct validity. The scale was distributed to 2012 school students in Grades 5 to 10. Factor analysis using varimax rotation yielded four factors interpretable as depressed mood, hopelessness, lack of pleasurable activities, and physiological symptoms.

Irrational beliefs in major depression and generalized anxiety disorders in an Iranian sample: a preliminary study.

Previous research on Rational Emotive Theory using western samples has shown that irrational belief systems are associated with emotional disorders such as anxiety and depression. In a replication of this work the present study was conducted to compare the scores of 29 clinically depressed, 31 clinically anxious, and 34 normal controls on the Irrational Beliefs Test in an Iranian sample. Consistent with Ellis's theory, depressed and anxious patients scored higher than the controls on scores for the full scale and all 10 subscales of the Irrational Beliefs Test.

Cerebral lateralization of global-local processing in left- and right-handed people.

Cerebral lateralization of global-local processing of 70 left-handed and 70 right-handed students was compared using a computerized global-local task in a half-visual field paradigm. Analysis showed that left-handed individuals were slower than right-handed individuals in processing Globally Directed stimuli presented to the left visual field (right hemisphere). In addition, left-handed individuals showed smaller local superiority in the left hemisphere to the right-handed individuals.