Publications by authors named "Mohammad Shahriar"

Residents of Bangladesh are exposed to numerous chemicals due to local industries, including dyeing mills, cotton mills, and the use of biomass in daily cooking. It is, therefore, important to characterize the exposome and work to identify risk factors of exposure. We used silicone wristband passive samplers to evaluate exposure to volatile and semi-volatile organic compounds in a sample of 40 children in the Araihazar upazila of Bangladesh.

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  • Generalized anxiety disorder (GAD) is a common mental illness characterized by uncontrollable worries, influenced by various factors like genetics, environment, and daily stress.
  • A study involving 50 GAD patients and 38 healthy controls found that GAD patients had significantly higher serum levels of epidermal growth factor (EGF), which correlated positively with the severity of their symptoms.
  • While EGF levels showed potential as a diagnostic biomarker for GAD, serum levels of stromal cell-derived factor-1 (SDF-1) did not significantly differ between GAD patients and healthy controls.
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Background: Lung cancer remains a leading cause of cancer-related deaths globally, with increasing incidence among females. Sex differences in lung cancer risk and outcomes are influenced by various factors, including biological characteristics. In Bangladesh, where lung cancer mortality rates are high, patients often present at advanced stages.

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Telomere length is associated with chronic diseases and in younger populations, may represent a biomarker of disease susceptibility. As growing evidence suggests that environmental factors, including metals, may impact telomere length, we investigated the association between 17 metals measured in toenail samples and leukocyte relative telomere length (RTL), among 472 five- to seven-year-old children enrolled in the Bangladesh Environmental Research in Children's Health (BiRCH) cohort. In single exposure linear regression models, a doubling of arsenic (As) and mercury (Hg) (μg/g) were associated with a -0.

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Exposure to inorganic arsenic (As) is recognized as a risk factor for non-melanoma skin cancer (NMSC). We followed up with 7000 adults for 6 years who were exposed to As. During follow-up, 2.

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Background: Despite being preventable, cervical cancer remains a leading cause of mortality among Bangladeshi women. This article addresses the trends in Bangladesh's response to the World Health Organization's (WHO) request for the eradication of cervical cancer within the nation.

Discussion: When it comes to cervical cancer, healthcare institutions need to be concerned in terms of protocols for diagnosis and treatment, staff education, and available resources.

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Background: Major depressive disorder (MDD) is a common and debilitating mental illness characterized by persistent feelings of sadness, hopelessness, and a lack of interest in daily activities. The objective of this study was to investigate whether levels of macrophage inflammatory protein-1β (MIP-1β) and macrophage chemoattractant protein-2 (MCP-2) in the blood were associated with the pathophysiology and development of MDD compared to healthy controls (HCs).

Methods: This case-control study was conducted involving 50 MDD patients and 38 HCs.

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  • Type 2 diabetes (T2D) is a complex disease influenced by various genetic factors and molecular mechanisms that vary by cell type and ancestry.
  • In a large study involving over 2.5 million individuals, researchers identified 1,289 significant genetic associations linked to T2D, including 145 new loci not previously reported.
  • The study categorized T2D signals into eight distinct clusters based on their connections to cardiometabolic traits and showed that these genetic profiles are linked to vascular complications, emphasizing the role of obesity-related processes across different ancestry groups.
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Salt enhances the taste as well as the nutritional value of food. Besides, several reports are available on the incidence and epidemiology of various illnesses in relation to salt intake. Excessive salt consumption has been found to be linked with high blood pressure, renal disease, and other cardiovascular disorders due to the result of vascular inflammation.

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Background: Readymade garment workers globally experience distinctive vulnerabilities at the workplace. The situation is worse in many developing countries. However, there is a lack of scientific evidence about the health and safety of garment workers in the workplace.

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This paper is a follow-up to a recent work by the authors on recoverable UAV-based energy-efficient reconfigurable routing (RUBER) scheme for addressing sensor node and route failure issues in smart wireless livestock sensor networks. Time complexity and processing cost issues connected to the RUBER scheme are consequently treated in this article by proffering a time-aware UAV-based energy-efficient reconfigurable routing (TUBER) scheme. TUBER scheme employs a synchronized clustering-with-backup strategy, a minimum-hop neighborhood recovery mechanism, and a redundancy minimization technique.

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Background: Previous studies have suggested the involvement of an activated inflammatory process in major depressive disorder (MDD), as altered expression of inflammatory cytokines is observed in depression. This alteration can be the cause or a consequence of MDD. However, acknowledging inflammatory cytokines as prospective biomarkers would aid in diagnosing or guiding better therapeutic options.

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Background: Major Depressive Disorder (MDD) is a common mental ailment and is the primary reason for disability. It manifests a severe impact on moods, thoughts, and physical health. At present, this disorder has become a concern in the field of public health.

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  • * As COVID-19 cases and deaths decrease, various healthcare strategies, including dedicated units and telehealth, have been implemented to manage the pandemic, alongside advancements in treatment and widespread vaccination.
  • * The World Health Organization officially declared the end of the COVID-19 pandemic phase on May 5, 2023, prompting a shift in focus towards managing other health challenges and returning to pre-pandemic life.
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Altered levels of peripheral inflammatory and proinflammatory cytokine markers affect the different clinical stages of major depressive disorder (MDD). A concrete understanding of the causal mechanism of MDD is a prerequisite in developing treatment strategies and preventive plans. Here we aimed to conduct an updated systematic review and meta-analysis of studies assessing the association of C-reactive protein (CRP), INF-γ, MCP-1, and TNF-α in the peripheral fluid of drug-naïve MDD patients and healthy controls (HCs).

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Background: We conducted a clean fuel intervention trial (Bangladesh Global Environmental and Occupational Health (GEOHealth) (NCT02824237) with liquefied petroleum gas (LPG) for 26 months among rural Bangladeshi women chronically exposed to household air pollution (HAP) from biomass fuel (BMF) use. We aimed to evaluate the effect of HAP reduction following LPG intervention on immune response outcome.

Methods: We supplied LPG cook stove and refills in cylinder in 200 households for 26 months.

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Marburg virus disease (MVD) caused by the Marburg virus has a high mortality rate. fruit bats act as the natural reservoir host of the virus. But it can also potentially be transmitted from person to person through direct contact with body secretions.

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  • The study examines differences in serum levels of the pro-inflammatory cytokine leptin and the neurotrophic factor EGF between patients with major depressive disorder (MDD) and healthy controls (HCs), revealing lower EGF levels in MDD patients.* -
  • A total of 205 MDD patients and 195 HCs were evaluated, using DSM-5 for diagnosis and the HAM-D scale for measuring depression severity; results indicated elevated HAM-D scores in MDD patients but no correlation between EGF levels and depression severity.* -
  • While the study suggests that lower EGF levels may influence the development of depression, it concludes that these EGF level changes do not correlate with the severity of the depressive condition.*
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Objectives: Numerous earlier studies have stated an association between major depressive disorder (MDD) and altered expression of inflammatory process. However, it still needs to determine whether the alteration of cytokines is the causative factor or a consequence of this disorder. Therefore, we attempted to evaluate the role of the pro-inflammatory cytokine IL-2 in the pathophysiology of depression.

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  • Mpox (monkeypox) has become a global health concern, leading to a public health emergency declaration by the WHO, with smallpox vaccines recommended for prevention.
  • A web-based survey conducted among adult males in Bangladesh assessed their perception of the Mpox vaccine and their intention to get vaccinated, revealing that over 60% had a favorable perception and medium intention.
  • The study found that sociodemographic factors, such as education level, age, and marital status, significantly influenced perceptions and intentions regarding the Mpox vaccine.
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Objective: There is a lack of established biological, psychological, social, and digital markers for the prediction, identification, and stratification of patients with major depressive disorder (MDD). We therefore aimed to evaluate serum nerve growth factor (NGF) in MDD patients.

Methods: In this case-control study, we recruited MDD patients and age- and sex-matched healthy controls (HCs).

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Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes. To characterise the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study (GWAS) data from 2,535,601 individuals (39.7% non-European ancestry), including 428,452 T2D cases.

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