Biotransformation of benzaldehyde into L-phenylacetylcarbinol using magnetic nanoparticles-coated yeast cells.

Objectives: The yeast cells were coated with FeO magnetic nanoparticles and employed as biocatalyst for the microbial biotransformation of benzaldehyde into L-phenylacetylcarbinol (L-PAC).

Results: Saccharomyces cerevisiae CEN.PK113-7D yeast cells were coated with magnetic nanoparticles to facilitate the cells separation process.

Design, Synthesis, Biological Evaluation and Molecular Modeling Study of Novel Indolizine-1-Carbonitrile Derivatives as Potential Anti-Microbial Agents.

A novel one-pot two step tandem reaction for the synthesis of indolizine-1-carbonitrile derivatives (5a-i) was identified. The route comprises 1,3-dipolar cycloaddition reaction of aromatic aldehyde derivatives (1a-i), malononitrile (2) and 1-(2-(4-bromophenyl)-2-oxoethyl)-2-chloropyridin-1-ium (4) under ultrasound irradiation at room temperature in the presence of triethylamine at acetonitrile. The product compounds were tested against bacteria and fungi.

Cultivation of newly isolated microalgae Coelastrum sp. in wastewater for simultaneous CO fixation, lipid production and wastewater treatment.

Cultivation of microalgae in wastewater is a promising and cost-effective approach for both CO biofixation and wastewater remediation. In this study, a new strain of Coelastrum sp. was isolated from cattle manure leachate.

A very rare case of eyelid metastasis originating from lung adenocarcinoma.

Purpose: To report a very rare eyelid mass confirmed to be a metastasis from lung adenocarcinoma.

Methods: A 68-year-old man had a two-month history of a large nodule in the right upper eyelid. He was a known case of lung adenocarcinoma since 2 years without a history of systemic metastasis.

Ultrasound-assisted 1,3-dipolar cycloaddition and cyclopropanation reactions for the synthesis of bis-indolizine and bis-cyclopropane derivatives.

Ultrasound irradiation can promote the 1,3-dipolar cycloaddition reaction of 2-chloropyridinium ylides with 2-benzylidenemalononitrile or 2,2'-(1,4-phenylenebis(methanylylidene))dimalononitrile, to afford the indolizine and bis-indolizine derivatives respectively. While the reaction of pyridinium ylides with 2-benzylidenemalononitrile or 2,2'-(1,4-phenylenebis(methanylylidene))dimalononitrile under ultrasound irradiation provided, in an unusual manner, cyclopropane and bis-cyclopropane derivatives, respectively. These cycloaddition and cyclopropanation reactions were carried out in the presence of triethylamine, in acetonitrile, at room temperature.