Publications by authors named "Mohammad Sadegh Keshmiri"

Background: The coronavirus 2019 (COVID-19) has affected the lives of many people worldwide. Patients with chronic underlying morbidities are vulnerable to get the severe form of the infection. The goal of this study was to evaluate the outcome of patients with pulmonary arterial hypertension during the COVID-19 pandemic in Iran.

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Remdesivir is effective against SARS-Cov-2 with little evidence of its adverse effect on the cardiac system. The aim of the present study is investigating the incidence of bradycardia in COVID-19 patients treated with Remdesivir. This prospective longitudinal study was conducted in a tertiary center on COVID-19 patients for Remdesivir therapy.

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Background: The coronavirus disease 2019 (COVID-19) has caused a global pandemic with a significant negative impact on health worldwide. Although it primarily involves the respiratory tract system, cardiovascular complications, particularly thrombotic events are increasingly reported and are associated with adverse outcomes.

Case Summary: We describe a 30-year-old male who presented with exaggerated dyspnea and hypoxia with mild constitutional symptoms along with a positive PCR test for SARS-CoV-2.

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After the outbreak of the novel coronavirus at the end of December 2019 in China, it has become a global pandemic. Clinical manifestation of coronavirus disease 2019 (COVID-19) has a wide range of presentations from asymptomatic to severe multi-organ involvement. Hemoptysis appears to be one of the major manifestations of severe acute respiratory syndrome that is related to COVID-19 infection.

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Pulmonary artery hypertension (PAH) occurs when mean pulmonary artery pressure (PAP) is higher than 25 mmHg in rest or 30 mmHg during activity. Idiopathic pulmonary artery hypertension (IPAH) is defined as PAH without a definite reason. The IPAH is a rare disease with a high mortality rate if left untreated.

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Background: The study aimed to evaluate the effectiveness and safety of BAE in TB patient with massive hemoptysis and evaluate the recurrence rate of hemoptysis after BAE.

Materials And Methods: In this prospective study, 68 patients with moderate and severe hemoptysis due to active or old tuberculosis who underwent bronchial arteriography were included. CXR and CT scan were performed in all patients.

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Article Synopsis
  • This study investigates how liver dysfunction affects outcomes in heart failure patients undergoing heart transplant, using established risk-scoring systems originally designed for liver disease.
  • Data from 60 patients who received heart transplants were analyzed, revealing a notable increase in mortality risk associated with higher scores on the modified Model for End-Stage Liver Disease.
  • The findings suggest that the modified scoring system is a useful tool for predicting postoperative survival in patients with congestive hepatopathy undergoing cardiac transplant.
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Article Synopsis
  • A study involving 2,403 hospitalized COVID-19 patients in Iran investigated the risks of QTc prolongation and torsade de pointes (TdP) associated with various repurposed drugs used for treatment.
  • The primary findings indicated that 11.2% of patients experienced critical QTc prolongation and 0.38% experienced TdP, with higher risks linked to certain factors like female gender and specific medications.
  • The study concluded that while significant QT prolongation was observed with the medications, serious arrhythmias like TdP were infrequent, particularly with hydroxychloroquine and lopinavir-ritonavir.
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Background: Massive hemoptysis which is presented in advanced lung diseases is a life-threatening condition. Bronchial artery embolization as a minimally invasive procedure is the treatment of choice either in first or recurrent hemoptysis. This study aimed to assess the early and late efficacy of bronchial angioembolization (BAE) without microcatheter.

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Background: Predicting prognosis is a cornerstone in management of pulmonary arterial hypertension. Hemodynamic parameters are among the robust indicators of right ventricular function and prognosis. In this study we have investigated the association of a simple hemodynamic parameter with clinical worsening in pulmonary arterial hypertension.

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