Publications by authors named "Mohammad S Najafi"

Chronic obstructive pulmonary disease (COPD) is a common condition that complicates major surgeries like coronary artery bypass grafting (CABG). This study aims to evaluate the impact of COPD on the outcome of CABG. A registry-based retrospective cohort study included individuals who received CABG between 2009 and 2016.

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Background: The benefits and risks of coronary artery bypass grafting (CABG) in octogenarians remain unclear. This study aimed to identify the predictors of increased risk of all-cause mortality in octogenarian patients after CABG.

Methods: We retrospectively analyzed the data of 1636 octogenarians who underwent isolated elective on-pump CABG between 2007 and 2016.

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Background & Aim: Timely identification of the patients requiring intensive care unit admission (ICU) could be life-saving. We aimed to compare different machine learning algorithms to predict the requirements for ICU admission in COVID-19 patients.

Methods: We screened all patients with COVID-19 at six academic hospitals in Tehran comprising our study population.

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Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women. Dyslipidemia is a prevalent metabolic abnormality in individuals with PCOS. Moreover, vitamin D deficiency is widespread across all societal strata, with a particularly heightened prevalence observed in patients afflicted with PCOS.

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Article Synopsis
  • Digital Polymerase Chain Reaction (dPCR) is a highly efficient method for quantifying DNA and identifying copy number variants, particularly useful in non-invasive prenatal testing for conditions like trisomy 21, 18, and 13.
  • A systematic review analyzed 9 studies to assess dPCR's effectiveness, showing high pooled sensitivity (98%) and specificity (99%) for trisomy 21 when compared to traditional karyotyping.
  • The results indicate dPCR is a promising alternative to next-generation sequencing for prenatal testing, although more research is needed to confirm its effectiveness for trisomies 18 and 13.
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Purpose: Obesity is a chronic low-grade inflammatory condition with increasing global prevalence and is associated with cardiovascular diseases. In this study, we aimed to investigate the prevalence of obesity in the Tehran cohort study (TeCS) population.

Methods: We used the data collected by systematic random sampling during the recruitment phase of TeCS.

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Introduction: Reduced left ventricular ejection fraction (LVEF) is a well-known predictor of adverse events after cardiac surgery. We aimed to assess the outcomes in patients with low LVEF undergoing coronary artery bypass graft.

Methods: In this retrospective cohort, we included all patients with left ventricular ejection fraction ≤ 40 who underwent coronary artery bypass grafting between March 2007 and March 2016 (with a median follow-up of nine years) at Tehran Heart Center.

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Background: Opium consumption has been an overlooked health issue in the Iranian population, and the prognostic role of opium consumption in patients undergoing coronary revascularization is unknown.

Hypothesis: We aimed to assess the association between opium consumption and long-term cardiovascular outcomes after percutaneous coronary intervention (PCI).

Methods: We screened 2203 consecutive patients who underwent elective PCI between April 2009 and April 2010 at Tehran Heart Center.

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Aim: We systematically reviewed and meta-analyzed the predictors of major adverse cardiac and cerebrovascular events (MACE/MACCE) in older adults who underwent PCI.

Methods: Three databases, PubMed, Embase, and Scopus, were searched for observational studies considering the out-of-hospital MACE/MACCE in adults ≥ 60 years old with coronary artery disease (acute or chronic) who underwent PCI. Studies were eligible if they had determined at least two statistically significant predictors of MACE/MACCE by multivariable analysis.

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Article Synopsis
  • SARS-CoV-2, the virus behind COVID-19, has evolved into several variants since its emergence in late 2019, including the notable Omicron and Delta variants.
  • A systematic review assessed the differences between these variants by analyzing 58 articles and over 10,000 pieces of evidence.
  • Findings indicate that Omicron is linked to lower hospitalization and severity rates compared to Delta, highlighting the need for ongoing monitoring and updated vaccination strategies.
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Background: In the current study, we aimed to report the short- and mid-term outcomes of patients undergoing valve-sparing aortic root reimplantation (VSARR) and our center's experience with the procedure.

Methods: Forty patients with aortic root aneurysms underwent VSARR at our center from 2010 until 2022. We retrospectively reviewed the medical records of these patients and extracted the relevant data.

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Article Synopsis
  • Inguinal herniation of the ureter is a rare complication that can result in symptoms like groin pain and obstructive uropathy, emphasizing the need for awareness in diagnosis.
  • A case study details a 75-year-old man with persistent left inguinal pain, initially thought to have an indirect inguinal hernia, but imaging revealed a tubular structure that was ultimately identified as an ectopic ureter.
  • The findings stress the importance of comprehensive clinical evaluations and appropriate imaging techniques prior to surgery to avoid misdiagnoses and complications.
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Key Message:

Abstract: Usefulness of preoperative tissue sampling and pathology diagnoses in thyroid tumors were accepted worldwide. We investigate the role of Core needle biopsy (CNB) in the thyroid nodules lesions when FNA results are nondiagnostic. We conducted a cross-sectional study to evaluate twenty-six CNBs results of suspicious malignant thyroid nodules with nondiagnostic repeated fine needle aspiration.

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Being in vicinity of vast deserts, the west and southwest of Iran are characterized by high levels of dust events, which have adverse consequences on human health, ecosystems, and environment. Using ground based dataset of dust events in western Iran and NCEP/NCAR reanalysis data, the atmospheric circulation patterns of dust events in the Arabian region and west of Iran are identified. The atmospheric circulation patterns which lead to dust events in the Arabian region and western Iran were classified into two main categories: the Shamal dust events that occurs in warm period of year and the frontal dust events as cold period pattern.

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