Antihypertensive Effects of Hydroalcoholic Extract of Fruit in Rats with Renovascular Hypertension: An Experimental Mechanistic Study.

Background: Hawthorn species decreases blood pressure and relaxes precontracted vessels. This study aimed at examining the antihypertensive effect and related mechanisms of hydroalcoholic extract of fruit in rats with renovascular hypertension.

Methods: Six groups of male Sprague-Dawley rats, each containing 6 to 8 rats, were studied.

The cardioprotective effects of resveratrol in rats with simultaneous type 2 diabetes and renal hypertension.

This study aimed at examining the cardioprotective effects of resveratrol in rats with simultaneous type 2 diabetes and renal hypertension. Eight groups (8-10 each) of male Sprague-Dawley rats, including a control, a diabetic, a renal hypertensive, a sham, a simultaneously hypertensive-diabetic receiving vehicle, and 3 simultaneously hypertensive-diabetic receiving resveratrol at 5, 10 or 20 mg/kg/day were used. After 4 weeks of treatment, blood pressure and glucose, and serum markers of oxidative stress were measured, and animals' hearts were used for isolated studies.

The effects of resveratrol in rats with simultaneous type 2 diabetes and renal hypertension: a study of antihypertensive mechanisms.

Background: Resveratrol has beneficial effects on cardiovascular system. This study aimed at examining antidiabetic and antihypertensive effects of resveratrol in rats with simultaneous type 2 diabetes and renal hypertension.

Methods: Eight groups (8-10 each) of male Spargue-Dawley rats, including a control, a diabetic (induced by streptozotocin and nicotinamide), a renal hypertensive (induced by placing plexiglas clips on the left renal arteries), a sham, a simultaneously hypertensive-diabetic receiving vehicle, and 3 simultaneous hypertensive-diabetic receiving resveratrol at 5, 10 or 20 mg/kg/day were used.

Synthesis of a phenylalanine imprinted polymer for attenuation of phenylalanine absorption via the gut in a murine hyperphenylalaninemia model.

Polymer technology plays an influential role in biomedical sciences. Molecular imprinting is a technique for preparation of polymers with structure-selective adsorptive properties. High selectivities of these materials have nowadays advanced to the point that they are being utilized for several biomedical applications such as drug delivery.

In vitro screening of different Allium sativum extracts on hydatid cysts protoscoleces.

This study was conducted to assess the protoscolicidal effect of garlic (Allium sativum) extract on protoscoleces of hydatid cysts in vitro. Viability of protoscoleces was determined, as the percent of viable protoscoleces to the total protoscoleces in 1 ml of the hydatid fluid, using eosin stain method. Four types of garlic extracts including: aquaus extract, chloroform extract (with two concentrations) and hydro-alcoholic extract along with cetrimide and silver nitrate as positive control, and normal saline as negative control, were used in this study.

Epidemiology of childhood burn injuries in Fars province, Iran.

Childhood burn injuries are a major environmental agent responsible for significant morbidity and mortality in Iran. Thus, the objective of this study was to analyze the epidemiology and current causative factors of hospitalized burn injuries among the approximately 1.6 million children between the ages of birth through 15 years residing in the Fars province of Iran.