Publications by authors named "Mohammad Reza Lashkarizadeh"

Article Synopsis
  • Albendazole has limited effectiveness against Echinococcosis, prompting research into improving treatment outcomes, particularly through the use of Sulfonated Graphene Oxide (S-GO) as a nanocarrier.
  • In the study, protoscoleces were treated with different agents, and it was found that S-GO combined with Albendazole (S-GO-Albendazole) enhanced gene expression and was 18% more effective at reducing the survival of protoscoleces compared to Albendazole alone.
  • Despite S-GO's lack of strong lethality on its own, it significantly improved Albendazole's efficacy, suggesting its potential as a nanocarrier, but further studies are necessary to assess
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Background: Cystic echinococcosis (CE) or hydatid disease is a global public health concern which imposes considerable economic costs on the communities in endemic regions. CE surveillance data are not adequately reliable. The present study reports the development and outcomes of a CE registry in Iran.

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Background: Fascioliasis, caused by Fasciola hepatica, is a neglected zoonotic food-borne trematodiasis. The Caspian littoral in northern Iran is endemic for the disease, and human fascioliasis is well-known in that region. In the present study, we report the diagnosis, identification, and clinical management of a human case of fascioliasis associated with common bile duct (CBD) obstruction from a non-endemic remote area in southeastern Iran.

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Our knowledge on the susceptibility of humans to different genotypes of the zoonotic tapeworm and the genetic make-up of the cysts in multi-organ involvements is limited. This study aimed to identify the genotype profile of in patients undergoing hydatid surgery in an endemic area for cystic echinococcosis (CE) in southeastern Iran. Individuals who underwent hydatid cyst surgery were included in this study.

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Background: Nowadays pain control is one of the most important challenges for physicians, surgeons and anesthesiologists. New drugs and procedures to control pain have always been a major topic for researches.

Aim: In this study, we evaluated the effects of preoperative pregabalin administration on relieving postoperative pain after thoracotomy surgery.

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Background: Opium addiction alters immune responses to stresses such as an injury due to changing the secretion of cytokines. The present study assessed the effect of opium addiction on the cytokines [tumor necrosis factor α (TNFα), interferon-γ (IFN-γ), interleukin-4 (IL-4), and IL-10] before and after laparotomy.

Methods: Male rats were randomly divided into control and opium addicted (n = 20).

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Background: Surgery is the preferred treatment for hydatid cyst (cystic echinococcosis, CE). At present, various scolicidal agents have been used for inactivation of protoscoleces during surgery, but they are associated with adverse side effects. The aim of the present study was to evaluate the scolicidal effects of amphotricin B, Silver nano particles, Foeniculum vulgare Mill, essential oil and hypertonic saline against protoscoleces of hydatid cyst on an in vitro model.

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Background: Tracheostomy site infection can cause numerous problems. Absorbent foam dressing may be able to prevent proliferation of infectious microorganisms by absorbing the tracheostomy stoma exudate. This study aimed to compare the efficacy of absorbent foam with gauze dressing for prevention of tracheostomy site infection.

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Objective(s): Gastroesophageal Reflux Disease (GERD) is one of the most common digestive disorders that frequently lead to pulmonary complications due to gastric fluid aspiration. In the present experimental study, chronic aspiration of gastric fluid, its components and bile salts in rat lung was performed to find out the main factor(s) causing pulmonary complications of gastric fluid aspiration.

Materials And Methods: Forty eight male rats weighted 250-300 g were selected in six groups.

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Fibroadenoma is a common benign tumor observed during the second and third decades of life. Malignancy transformation in the epithelial component of a fibroadenoma is rare and can occur 20 years after its diagnosis. Mammographic findings in this phenomenon include indistinct margins and microcalcifications.

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About 8% of the general population suffers from autoimmune diseases, from which 78% are women. One of the most important causes of thyroid diseases is autoimmunity in origin, and it seems that people with thyroid diseases present more signs of asthma. This study was therefore designed to investigate the frequency of autoimmune thyroid diseases in women suffering from bronchial asthma.

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Askin's tumor is a rare neoplasm of the chest wall with a dismal prognosis and is usually observed in young subjects. We describe a 15-year-old female with massive hemoptysis who had an extensive thoracopulmonary tumor on chest CT. She underwent bronchoscopy which showed the location of the tumor in the bronchus intermedius.

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Objective: To assess the outcome of surgical management of mycotic false aneurysms due to local injury after intravenous injection of drugs.

Study Design: Case series.

Place And Duration Of Study: Department of Surgery, Kerman Medical School of Sciences, Kerman, Iran, from July 2001 to June 2009.

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Background: Early tracheostomy can reduce the time required for mechanical ventilation, the duration of ICU stay, and treatment expenses. Choosing the optimal time for tracheostomy in patients with severe head injury is therefore important. The purpose of this study was to find the optimal time for tracheostomy according to Glasgow Coma Scale (GCS).

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