Publications by authors named "Mohammad Reza Abdosalehi"

Article Synopsis
  • The study focused on evaluating antibiotic resistance in Gram-positive bacteria from hospital-acquired infections in pediatric patients over a six-month period.
  • It utilized methods like Kirby-Bauer disk diffusion and PCR techniques for antmicrobial profiling and genotyping of the bacteria.
  • Findings revealed high resistance rates, particularly to penicillin (96.3%) and ciprofloxacin (100%), with significant prevalence of MRSA and a need for improved infection control measures due to clonal spread.
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Background And Aim: Hospital-acquired infection (HAI) is a major problem worldwide. Understanding patterns of bacterial etiology and antibiotic susceptibility is vital to combating HAI. Besides, typing of isolates is important to establish the intra-hospital surveillance of resistant clones.

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Introduction: Klebsiella pneumoniae is a common cause of nosocomial infections; however, there is limited information in Iran regarding nosocomial outbreaks due to extended-spectrum β-lactamase (ESBL) producing K pneumoniae strains, particularly using molecular methods. The present study focused on the molecular mechanism of ESBL resistance and genetic relatedness in K. pneumoniae isolates causing nosocomial infections in an Iranian referral hospital.

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