Publications by authors named "Mohammad R Baghaipour"

Article Synopsis
  • The study assessed the effectiveness of two bleeding assessment tools (ISTH-BAT and EN-RBD-BSS) in identifying patients with congenital fibrinogen deficiencies (CFDs) among 100 Iranian participants.
  • Results showed a moderate correlation between the two tools, with both successfully identifying around 70% of patients with fibrinogen deficiencies.
  • The findings suggest that both assessment tools are useful for evaluating bleeding severity in CFD patients and may help in clinical decision-making.
View Article and Find Full Text PDF
Article Synopsis
  • Congenital combined bleeding disorders (CBDs) are rare and often related to consanguineous marriages, presenting symptoms from minor bleeding to severe complications.
  • The study evaluated 450 patients at the Iranian Comprehensive Hemophilia Care Center, identifying FV-FVII deficiency and FVII-FX deficiency as the most prevalent types among the analyzed cases.
  • Findings highlighted that a significant number of patients experienced postoperative bleeding, and the majority received on-demand treatment rather than preventative care, indicating a need for better management strategies in Iran.
View Article and Find Full Text PDF

Coronavirus disease 2019 (COVID-19) is a new medical challenge for all individuals, especially for those with underlying disorders, such as congenital bleeding disorders (CBDs). Therefore, the pandemic might significantly change the behaviour of patients with CBDs and results in some challenges. In the present study, we assessed the main challenges of COVID-19 infection to patients with CBDs.

View Article and Find Full Text PDF

Introduction: Congenital fibrinogen disorders (CFDs) comprise the quantitative and qualitative fibrinogen molecule abnormalities that are caused by fibrinogen gene mutations. The objective of this cohort research was to study the molecular and clinical profiles of patients with CFDs.

Materials And Methods: Genomic DNA Sanger sequencing of 14 Iranian patients was performed to determine CFDs-causing mutations.

View Article and Find Full Text PDF

One important complication of patients with severe haemophilia A is the formation of inhibitory antibodies to factor VIII (FVIII). Immune tolerance induction (ITI) is the treatment of choice for patients with inhibitors, but this approach is successful in about 60% of patients. Treatment of acute bleeding in patients with inhibitors is one of the greatest challenges in haemophilia management and is costly.

View Article and Find Full Text PDF