Although studies support a positive correlation between temperature and stone risk, the precise relationship between these factors has not been elucidated. We modeled the current distribution of urolithiasis prevalence in Iran using 26 bioclimatic, climatic and topographic variables based on two multivariate linear regression models in geographical information system. The impact of climate change on the stone prevalence was predicted under the projections of GFDL-ESM2G, CCSM4 and HadGEM2-ES climate models by mid-century (2050).
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