Two-step GLIM approach using NRS-2002 screening tool vs direct GLIM criteria application in hospital malnutrition diagnosis: A cross-sectional study.

Background: The two-step Global Leadership Initiative on Malnutrition (GLIM) approach was recently introduced to malnutrition diagnosis in a hospital setting. This study compares the diagnostic performance of this approach that uses the Nutritional Risk Screening-2002 (NRS-2002) as a screening tool and the direct application of GLIM malnutrition diagnostic criteria in hospitalized patients.

Methods: This cross-sectional study involved 290 adult and older adult patients who were hospitalized.

Effects of zinc supplementation on sleep quality in humans: A systematic review of randomized controlled trials.

Background And Aims: Alternative therapies, such as zinc supplementation, have been explored as potential interventions for sleep disorders. However, the efficacy of zinc supplementation in improving sleep quality remains uncertain. This systematic review aims to examine the impacts of zinc supplementation on sleep quality in humans.

Cranial remolding orthosis for children with deformational skull deformities: A systematic review on the factors affecting success and duration of treatment.

Deformational plagiocephaly, deformational brachycephaly, and deformational scaphocephaly are the most common types of skull deformities during the first year of life. Using a cranial remolding orthosis (CRO) can have an important role in achieving a satisfactory level of improvement in symmetry and proportion of the deformed skulls. However, there is no consensus on the most important parameters for the success or length of treatment with a CRO.

Cell therapy for retinal degenerative disorders: a systematic review and three-level meta-analysis.

Background: Retinal degenerative disorders (RDDs) cause vision loss by damaging retinal neurons and photoreceptors, affecting individuals of all ages. Cell-based therapy has emerged as an effective approach for the treatment of RDDs with promising results. This meta-analysis aims to comprehensively evaluate the efficacy of cell therapy in treating age-related macular degeneration (AMD), retinitis pigmentosa (RP), and Stargardt macular degeneration (SMD) as the most prevalent RDDs.

Adherence to the nordic diet is associated with anxiety, stress, and depression in recovered COVID-19 patients, a case-control study.

Background: Follow-up of COVID-19 recovered patients to discover important adverse effects on other organs is required. The psychological health of COVID-19 patients may be affected after recovery.

Aim: We aimed to evaluate the association between adherence to the Nordic diet (ND) and psychological symptoms caused by COVID-19 after recovery.

The association of hematological inflammatory markers and psychological function in COVID-19 patients: A cross-sectional study.

Mental health disorders are linked to systemic inflammation. Due to high inflammation and mental health disorders in COVID-19 patients, we aimed to investigate the relationship between blood inflammatory markers such as red cell distribution width to platelet ratio (RPR), platelet-lymphocyte ratio (PLR), neutrophil/lymphocyte ratio (NLR), red cell distribution width (RDW), white blood cell (WBC), and psychological function in COVID-19 patients. In the current cross-sectional study, neuro-psychological function, and a complete blood count (CBC) were measured on 120 COVID-19 patients aged >30 years from the Imam Reza Hospital in Mashhad, Iran.

Comparison of Postoperative Pain and Clinical Outcomes of Total Knee Arthroplasty Among Patients with Rheumatoid Arthritis and Osteoarthritis Referred to Clinic or Emergency Department.

Background: Total knee arthroplasty (TKA) is among the most frequent orthopedic procedures. TKA has been shown to provide significant benefits to patients with rheumatoid arthritis (RA) and osteoarthritis (OA). We hypothesized that patients undergoing primary TKA with diverse preoperative diseases would have varying expectations for both pain and function following TKA.

Nanoparticle-mediated delivery of microRNAs-based therapies for treatment of disorders.

miRNAs represent appropriate candidates for treatment of several disorders. However, safe and efficient delivery of these small-sized transcripts has been challenging. Nanoparticle-based delivery of miRNAs has been used for treatment of a variety of disorders, particularly cancers as well as ischemic stroke and pulmonary fibrosis.

MnCoO/NiCoO/rGO as a Catalyst Based on Binary Transition Metal Oxide for the Methanol Oxidation Reaction.

The demands for alternative energy have led researchers to find effective electrocatalysts in fuel cells and increase the efficiency of existing materials. This study presents new nanocatalysts based on two binary transition metal oxides (BTMOs) and their hybrid with reduced graphene oxide for methanol oxidation. Characterization of the introduced three-component composite, including cobalt manganese oxide (MnCoO), nickel cobalt oxide (NiCoO), and reduced graphene oxide (rGO) in the form of MnCoO/NiCoO/rGO (MNR), was investigated by X-ray diffraction (XRD), scanning electron microscope (SEM), and energy-dispersive X-ray (EDX) analyses.

Eating frequency has an inverse correlation with adiposity measures and non-invasive arterial stiffness parameters in healthy adult people.

Background: Lifestyle modifications have been recommended as an essential treatment approach for cardiovascular diseases. Recent studies have shown that eating frequency (EF) correlates with hypertension and related risk of organ damage. This study aimed to examine critical clinical implications to evaluate the association of EF with arterial stiffness parameters as an early marker of atherosclerosis manifestations.

The effect of pyridostigmine on post-stroke dysphagia: A randomized clinical trial.

Swallowing is one of the most complex functions of the central nervous system (CNS), which is controlled by different parts of the brain. Oropharyngeal dysphagia (OD) is one of the most common complications after stroke. Despite a variety of behavioral, compensatory, and rehabilitative methods, many stroke patients still suffer from swallowing disorders that adversely affect their quality of life (QOL).

The relationship between genetic variants associated with primary ovarian insufficiency and lipid profile in women recruited from MASHAD cohort study.

Background And Aim: Primary Ovarian Insufficiency (POI) is defined by the occurrence of menopause before the age of 40 years. It is often associated with cardiovascular disease (CVD). The purpose of this study was to explore the relationship between POI-associated genotypes cardiometabolic disorder risk factors.

Multi modal imaging in corneal edema after corneal collagen cross-linking (CXL); a case-based literature review.

Background: Keratoconus (KCN) is a common ectatic disorder of the cornea. Corneal collagen cross-linking (CXL) is used as an effective option to slowdown the disease progression. Although CXL is considered a safe procedure, corneal endothelial damage, especially in corneal thickness of less than 400 μm, has been reported.

The association between serum TSH concentration whithin the normal range and nutritional status in euthyroid pregnant women at the first trimester of gestation.

Background: Follow-up studies have shown an increased risk of thyroid dysfunction in individuals with normal serum thyroid-stimulating hormone (TSH) levels. Furthermore, the possible consequences of minor differences in thyroid function (without achieving poor thyroid function) in the risk of weight gain during pregnancy are questionable, too. The production of TSH is under the hypothalamus-pituitary control, and food is one of the most effective environmental agents that control hypothalamic-pituitary-thyroid axis activity.

The impact of non-coding RNAs on normal stem cells.

Self-renewal and differentiation into diverse cells are two main characteristics of stem cells. These cells have important roles in development and homeostasis of different tissues and are supposed to facilitate tissue regeneration. Function of stem cells is regulated by dynamic interactions between external signaling, epigenetic factors, and molecules that regulate expression of genes.

Key educational and research factors affecting the future of medical education discipline in Iran: A qualitative study.

Context: Along with the evolutions of medical sciences education, the importance of medical education discipline has gained more attention for keeping up with these evolutions. Therefore, paying attention to policymaking regarding the development of this discipline and its position in universities is very necessary.

Aims: This study has been done with the aim of investigating key educational and research factors affecting the future of medical education discipline in Iran.

The importance of intracellular bacterial biofilm in infectious diseases.

Various bacterial species, previously known as extracellular pathogens, can reside inside different host cells by adapting to intracellular modes by forming microbial aggregates with similar characteristics to bacterial biofilms. Additionally, bacterial invasion of human cells leads to failure in antibiotic therapy, as most conventional anti-bacterial agents cannot reach intracellular biofilm in normal concentrations. Various studies have shown that bacteria such as uropathogenic Escherichia coli, Pseudomonas aeruginosa, Borrelia burgdorferi,Moraxella catarrhalis, non-typeable Haemophilus influenzae, Streptococcus pneumonia, and group A Streptococci produce biofilm-like structures within the host cells.

Bacterial biofilm in colorectal cancer: What is the real mechanism of action?

Human colorectal cancer is the third most common cancer around the world. Colorectal cancer has various risk factors, but current works have bolded a significant activity for the microbiota of the human colon in the development of this disease. Bacterial biofilm has been mediated to non-malignant pathologies like inflammatory bowel disease but has not been fully documented in the setting of colorectal cancer.

Physical model for temperature-dependent dielectric properties of anisotropic nematic liquid crystals.

We derived a new analytic physical model for describing the temperature-dependent dielectric permittivities εe(T) and εo(T) in anisotropic mesophase molecules of nematic liquid crystals (NLCs). These temperature-dependent dielectric properties of NLCs could be explained by a six-parameter dielectric permittivity model, where the analytic dielectric permittivity curves of εe(T), εo(T), and Δε(T) from the model using the six parameters ε*, Aε, Bε, (Δε)o, λε, and T* showed excellent agreement with experimental data. The six-parameter dielectric permittivity model was compared to the conventional four-parameter refractive index model.

Composition of minerals and trace elements at Mamasani thermal source: A possible preventive treatment for some skin diseases.

Introduction: Some skin diseases are incurable and modern medicine can only control them. In addition, alternative treatment remedies including balneotherapy can be effective in improving skin conditions. However, there are only a limited number of studies on particular mineral or trace elements of mineral sources that have been identified in Iran.

Assessment of Diagnostic Value of Single View Dynamic Technique in Diagnosis of Developmental Dysplasia of Hip: A Comparison with Static and Dynamic Ultrasond Techniques.

Background: Developmental dysplasia of hip (DDH) is a common childhood disorder, and ultrasonography examination is routinely used for screening purposes. In this study, we aimed to evaluate a modified combined static and dynamic ultrasound technique for the detection of DDH and to compare with the results of static and dynamic ultrasound techniques.

Methods: In this cross-sectional study, during 2013- 2015, 300 high-risk infants were evaluated by ultrasound for DDH.

Seasonal-based temporal changes fluctuate expression patterns of TXS, DBAT, BAPT and DBTNBT genes alongside production of associated taxanes in Taxus baccata.

Environmental cues have synergistic or antagonistic regulatory roles on transcription activity and taxanes accumulation in yew, though DBAT activity is less influenced, could be accordingly a rate-limiting enzyme. The current work was undertaken to elucidate the consequences of some environmental cues (i.e.

Prevalence and Prognostic Impact of Wilms' Tumor 1 (WT1) Gene, Including SNP rs16754 in Cytogenetically Normal Acute Myeloblastic Leukemia (CN-AML): An Iranian Experience.

Background: The aim of this study was to evaluate the effect of Wilms' tumor 1 (WT1) gene mutations in adult cytogenetically normal acute myeloblastic leukemia (CN-AML) patients on survival and clinical outcome.

Patients And Methods: A total of 88 untreated Iranian adult patients with CN-AML were selected as a study group. Exons 7 (including the SNP rs16754), 8, and 9 as a WT1 gene hotspot region were evaluated by polymerase chain reaction and direct sequencing for detection of mutations.

Numerical simulation of the tumor interstitial fluid transport: Consideration of drug delivery mechanism.

The interstitial fluid transport plays an important role in terms of its effect on the delivery of therapeutic agents to the cancerous organs. In this study, a comprehensive numerical simulation of the interstitial fluid transport establishing 3D models of tumor and normal tissue is accomplished. Different shapes of solid tumors and their surrounding normal tissues are selected, by employing the porous media model and incorporating Darcy's model and Starling's law.

Epidemiology of hand injuries in children presenting to an orthopedic trauma center in southeast of iran.

Background: Hand injuries are among the most common childhood injuries. No study has been performed regarding the epidemiology of hand injuries in the pediatric population of Iran. This study aimed to examine the epidemiology of hand injuries among children in southeast of Iran.