Publications by authors named "Mohammad Moein Maddah"
Article Synopsis
- Prostate cancer, a common cancer in men, is influenced by various factors including age, genetics, and lifestyle, with mutations in the TP53 gene linked to poor patient outcomes.
- Research shows that men with TP53 mutations have significantly lower overall survival rates and faster disease progression compared to those without these mutations.
- Monitoring TP53 mutations is important in managing prostate cancer treatment, as they indicate a higher risk of death and disease progression.
Orexin neuropeptides have functional roles in hippocampal-dependent memory formation via the consolidation and retrieval of passive avoidance and spatial memories. The effects of these neuropeptides have been confirmed on the induction of long-term potentiation (LTP). The orexinergic system seems to have modulatory effects by sending projection fibers to several brain parts, such as the hippocampus and amygdala.
View Article and Find Full Text PDFBackground And Purpose: Adult Hope Scale is one of the most popular tools for hope measuring. The study aimed to evaluate the psychometric properties of the Persian Version of Hope Scale among Iranian patients with cancer.
Methods: In this methodological study, patients with cancer ( = 400) were recruited by convenience sampling from June to December 2019.
We aimed to develop a scale and evaluate this scale's validity and reliability to measure factors affecting people's knowledge and attitudes toward the pandemic breaking transmission chain. This exploratory mixed-method study was carried out in two phases: (1) item generation using literature reviews and interviews and, (2) item reduction by psychometric assessments of the developed scale. The face, content, construct (exploratory and confirmatory factor analysis), convergent, and discriminant validity of the scale were assessed in the Iranian population ( = 500) from March to June 2020.
View Article and Find Full Text PDFThe orexinergic system supposedly plays a role in stress circuits for arousing behaviors during anxiety, suggesting that it may play a role also in neural circuits mediating the compulsive behavior characteristic of obsessive-compulsive disorder (OCD). This study aims to investigate the roles of the orexinergic system in the development of OCD behaviors, using as preparation the induction of compulsive checking by chronic treatment with the D2/D3 agonist, quinpirole. Repeated injections of quinpirole (0.
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