The Effects of Thymoquinone Loaded in Alginate Scaffold on Bone Regeneration in Rabbit Mandible Defect.

Background: Thymoquinone (TQ) has some beneficial roles in bone repair. Local administration of the drugs by loading them into a scaffold leads to releasing higher concentrations of a drug in the appropriate position. This study was conducted to evaluate the effects of the local administration of TQ loaded in an alginate scaffold on bone regeneration in rabbit mandibular defect.