Publications by authors named "Mohammad M Tavakol"

This study presents a series of numerical simulations for airflow field and particle dispersion and deposition around a mannequin inside a ventilated room. A 3-D airway system of a volunteer subject with a large respiratory system was reconstructed from the nostril inlet to the end of the tracheobronchial tree 4th generation and was integrated into a standing mannequin at the center of a room. The room ventilation system supplied air through a diffuser and expelled air via a damper in three modes.

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  • Cyperus rotundus L., commonly known as purple nutsedge, is a prevalent invasive weed that has traditional medicinal uses, including anti-arthritic and antidiarrheal effects as well as treatment for CNS disorders like epilepsy and depression.
  • α-Cyperone, a key compound in Cyperus rotundus, has not been studied for its impact on microtubule assembly and dynamics, which are crucial in the context of chronic inflammation and diseases like Alzheimer’s.
  • Experimental results indicate that α-Cyperone significantly alters tubulin structure, reduces polymerization rates, and induces conformational changes, suggesting it may influence inflammatory processes at a cellular level.
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In 2007, the islet community was notified that the collagenase product most commonly used for human islet isolations contained bovine neural tissue contaminants. To minimize this potential hazard, we adapted our human islet processing procedure to use a GMP-manufactured, bovine neural tissue-free collagenase blend. Here, we describe the factors that we consider most important for achieving reproducible and clinically useable islet isolations using this product.

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  • A study evaluated the long-term risks associated with kidney donation from obese donors, finding no significant increase in renal dysfunction compared to non-obese donors over several years.
  • Both donor groups showed reduced kidney function relative to matched two-kidney control subjects, but there were no major differences in health outcomes, except that obesity correlated with higher rates of hypertension and dyslipidemia.
  • The findings support the continued use of healthy obese individuals as kidney donors while highlighting the importance of better health management and education for these donors post-surgery.
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