Background: Idiopathic normal pressure hydrocephalus (iNPH) is a disease that primarily affects the geriatric population. It was first introduced by Adams . in 1965.
View Article and Find Full Text PDFThe mammalian spinal cord functions as a community of cell types for sensory processing, autonomic control, and movement. While animal models have advanced our understanding of spinal cellular diversity, characterizing human biology directly is important to uncover specialized features of basic function and human pathology. Here, we present a cellular taxonomy of the adult human spinal cord using single-nucleus RNA sequencing with spatial transcriptomics and antibody validation.
View Article and Find Full Text PDFBackground: Hydrogen peroxide (HP) is routinely used in neurosurgical procedures to achieve surgical hemostasis. However, its safety profile is still debatable with various reports depicting range of adverse effects on neuronal tissue. The objective of this paper is to evaluate the safety and efficacy of HP as a hemostatic agent in normal neuronal tissue during neurosurgical procedures conducted on rats.
View Article and Find Full Text PDFIntroduction: Intracranial meningiomas account for 30% of all primary intracranial tumors. Surgical resection remains the mainstay of the treatment for meningiomas. The magnetic resonance of intracranial meningiomas has been largely discussed in many reports of the radiological and neurosurgical literature.
View Article and Find Full Text PDFObjective: To evaluate potential risk factors that can predict the development of hydrocephalus (HCP) in adult patients with intraventricular hemorrhage (IVH).
Methods: Retrospective analysis of all adult patients presented to King Fahad Medical City between 2004 and 2011 with intraventricular hemorrhage to evaluate different variables and their association with HCP.
Results: A total of 31 patients were included in the study, 14 patients (45.