Efficacy and Safety of Amiodarone and Propranolol in Pediatric Cardiology for Arrhythmia After Cardiac Surgery: A Retrospective Design Study.

Objectives The study evaluated the efficacy of antiarrhythmic pharmacotherapies in managing tachyarrhythmia episodes in pediatric patients with congenital heart diseases post-tricuspid valve repair, assessing reductions in haemodynamic parameters and symptomatic variables, and observing side effects. Methods From January 2020 to January 2024, this study reviewed data from 300 patients, aged up to 18 years, who experienced arrhythmia following cardiac surgery and received treatment with amiodarone, propranolol, or both. The information included demographic and anthropometric measures, haemodynamic parameters, and antiarrhythmic drugs used to treat arrhythmias before and after tricuspid valve repair.

Clinical and Nutritional Determinants of Extrauterine Growth Restriction Among Very Low Birth Weight Infants.

Purpose: To identify the clinical and nutritional factors associated with extrauterine growth restriction (EUGR) among very low birth weight infants (VLBW) in a tertiary hospital in Jordan.

Patients And Methods: We conducted a retrospective analysis of all VLBW infants admitted at King Abdullah University Hospital between July 2015 and June 2020. Clinical factors, nutritional intake, and growth parameters were collected and analyzed.

Neonatal mortality in Jordan: secondary analysis of Jordan Population and Family Health Survey (JPFHS) data.

Objective: This study aimed to analyze the 2009 Jordan Population and Family Health Survey (JPFHS) data to determine the level, trend, and distribution of neonatal mortality (NNM) in Jordan and determine its associated factors.

Methods: Nationally representative data on NNM were extracted from the JPFHS data. Using multivariate analyses, the strength of associations between 12 clinical/sociodemographic variables and neonatal mortality were quantified after controlling for potential confounders.

Prevalence and outcome of acute kidney injury, as defined by the new Kidney Disease Improving Global Outcomes guideline, in very low birth weight infants.

Aim: To evaluate the prevalence, risk factors and outcome of acute kidney injury (AKI) in very low birth weight (VLBW) infants.

Methods: In this retrospective study of VLBW infants, we analyzed the prevalence of AKI, as defined by changes in serum creatinine and urine output, associated risk factors and outcomes.

Results: A total of 293 VLBW infants (mean gestational age 28.

Severe Hypotension After Amlodipine Use for Hypertension in a Newborn on Beta Blocker Therapy for Thyrotoxicosis.

A 35-year-old woman with a 9-year history of Grave's disease delivered a male infant weighing 2,210 g at 32 weeks of gestation by caesarean section. The neonate developed thyrotoxicosis and, at the age of 24 h, was treated with oral carbimazole (500 µg every 8 h) and propranolol (2 mg/kg/day in two divided doses). He subsequently developed hypertension on day 4, which required therapy with amlodipine (0.

Pitfalls in measuring cerebrospinal fluid glycine levels in infants with encephalopathy.

In encephalopathic infants, cerebrospinal fluid hyperglycinemia and elevated cerebrospinal fluid to plasma glycine ratio are considered pathognomonic of nonketotic hyperglycinemia. To evaluate the significance of cerebrospinal fluid hyperglycinemia and elevated cerebrospinal fluid to plasma glycine ratio in acutely encephalopathic infants, a retrospective chart review of all cases of isolated elevation of cerebrospinal fluid glycine levels at Arkansas Children's Hospital from January 1995 to December 2000 was performed. Twenty-two patients (14 males) were included.

Methylenetetrahydrofolate reductase polymorphisms C677T and A1298C as maternal risk factors for Down syndrome in Jordan.

Background: The activity of the methylenetetrahydrofolate reductase (MTHFR) enzyme is regulated by the two polymorphisms C677T and A1298C, which reduce enzyme activity and result in hypomethylation of chromosomes that increase the risk of nondisjunction. These polymorphisms are suggested to be risk factors for Down syndrome (DS) in some populations.

Aim: The aim of this study was to test if C677T and A1298C polymorphisms are correlated to maternal risk of DS in Jordan.

Attitudes of graduating medical doctors toward using sex selection techniques in Jordan in 2009.

Objectives: The aim of this study was to describe the attitude of graduating medical doctors toward the use of sex selection techniques in Jordan in 2009. MATERIALS AND METHODS (DESIGN): A self-administered questionnaire was used to assess attitude toward using sex selection. Demographic variables, gender preference of future children, and score on attitude toward using technology scale were used as independent variables.

Factors affecting intention to breastfeed among Syrian and Jordanian mothers: a comparative cross-sectional study.

Background: Breastfeeding is considered the ideal method of infant feeding for at least the first six months of life. This study aimed to compare breastfeeding intention between Syrian and Jordanian women and determine factors associated with breastfeeding intention among pregnant women in these two countries.

Methods: A cross-sectional design was used to collect data from1200 pregnant women aged 18 years and above (600 participants from each country).

Effect of methotrexate on the survival of human lymphocyte cultures carrying MTHFR 677 (C>T) and MTHFR 1298 (A>C) mutations.

The correlations between the presence of MTHFR 677 (C>T) and MTHFR 1298 (A>C) mutations in human lymphocytes and the sensitivity of lymphocytes to methotrexate (MTX) were examined in cultures derived from 82 unrelated women, genotyped for these mutations by polymerase chain reaction-restriction fragment length polymorphism. Lymphocytes heterozygous for the mutant allele, MTHFR 677T, were significantly more sensitive to methotrexate than those carrying the homozygous wild-type allele, MTHFR677C, and those carrying either the mutant or the wild-type alleles in the polymorphic MTHFR 1298 site. In addition, the lymphocyte cultures carrying the mutant MTHFR 1298C allele were not different in their sensitivity to MTX from those cultures carrying the wild-type allele, MTHFR 1298A.

Clinical features of neonatal sepsis caused by resistant Gram-negative bacteria.

Background: Clinical features and outcomes of neonatal sepsis caused by resistant Gram-negative bacteria are not well described in Jordan. The aim of the present study was therefore to describe microbiology and clinical features, laboratory findings and outcomes of early- and late-onset Gram-negative neonatal sepsis.

Methods: All patients with Gram-negative bacteremia between July 2003 and June 2005 were retrospectively included.

Sex preference and interest in preconception sex selection: a survey among pregnant women in the north of Jordan.

Background: Preconception sex selection for non-medical reasons is a controversial issue in bioethics. Little research has described preferences for preconception sex selection among Arab populations. This study describes the sex preference and interest in employing sex selection techniques among pregnant women in northern Jordan.

Maternal periodontal status and preterm low birth weight delivery: a case-control study.

Objectives: To assess the association between severity and extent of maternal periodontal disease and preterm birth/low birth weight (PLBW) among women in the north of Jordan.

Methods: A total of 148 woman who gave preterm birth/low birth weight birth and 438 women with uncomplicated full term vaginal delivery were included in this study. Socio-demographic characteristics, antenatal history, medical history, and family medical history were collected through personal interview or abstracted from maternal records.

Renal impairment and hydronephrosis in a premature infant following morphine infusion: case report.

This is a case report of an association between morphine administration and occurrence of hydronephrosis with acute renal failure. This premature female infant born at 27 weeks of gestation had moderate hydronephrosis with acute renal impairment while receiving morphine infusion for pain management after chest-tube insertion. All these findings were reversed after stopping morphine and urinary catheterization.

Knowledge, attitude and practice of breastfeeding in the north of Jordan: a cross-sectional study.

Background: In Jordan, as in neighboring countries in the Middle East, higher education and higher employment rates in recent years among women have had an impact on traditionally based infant feeding. The objective of this study was to evaluate practice, knowledge and attitude to breastfeeding and to assess factors associated with breastfeeding among women in the north of Jordan.

Methods: A cross sectional study was carried out between 15 July 2003 and 15 August 2003.

Endogenous nitric oxide modulates responses of tissue and airway resistance to vagal stimulation in piglets.

The role of endogenous nitric oxide (NO) in modulating the excitatory response of distal airways to vagal stimulation is unknown. In decerebrate, ventilated, open-chest piglets aged 3-10 days, lung resistance (RL) was partitioned into tissue resistance (Rti) and airway resistance (Raw) by using alveolar capsules. Changes in RL, Rti, and Raw were evaluated during vagal stimulation at increasing frequency before and after NO synthase blockade with N(omega)-nitro-L-arginine methyl ester (L-NAME).