Objective: To investigate the association between plasma omega-3 levels and incident heart failure (HF) and to examine their relationship with total and cardiovascular (CV) mortality among patients with preexisting HF.
Patients And Methods: The UK Biobank is an ongoing prospective cohort study of individuals recruited in the United Kingdom between April 1, 2007, and December 31. 2010.
Introduction: Bronchogenic cysts (BCs) are congenital lesions from abnormal foregut development, usually located in the mediastinum or lungs. While often asymptomatic and benign, they can cause complications. Surgical excision is the definitive treatment.
View Article and Find Full Text PDFImportance: Sodium-glucose cotransporter-2 inhibitors (SGLT2is) are the first therapy shown to improve clinical outcomes for patients with heart failure (HF) and a left ventricular ejection fraction (LVEF) greater than 40%. Nationwide adoption of SGLT2is in the US since publication of the Empagliflozin Outcome Trial in Patients With Chronic Heart Failure With Preserved Ejection Fraction (EMPEROR-Preserved) in August 2021 is unknown.
Objective: To examine trends and hospital-level variation in SGLT2i adoption.
Importance: The Kansas City Cardiomyopathy Questionnaire (KCCQ) is a commonly used outcome in heart failure trials. While comparing means between treatment groups improves statistical power, mean treatment effects do not necessarily reflect the clinical benefit experienced by individual patients.
Objective: To evaluate the association between mean KCCQ treatment effects and the proportions of patients experiencing clinically important improvements across a range of clinical trials and heart failure etiologies.
Introduction: Cystic Echinococcosis (CE), caused by Echinococcus granulosus, primarily affects the liver and lungs, particularly in endemic regions. While commonly associated with gastrointestinal manifestations, CE can lead to severe complications that necessitate surgical intervention.
Case Presentation: A 53-year-old female was referred due to a prolonged history of exertional dyspnea that recently worsened.
Int J Surg Case Rep
November 2024
Introduction: Textiloma, or gossypiboma, is a rare oversight in thoracic surgery involving retained surgical sponges, with the potential for serious complications like chronic pain and infection. This case highlights a 29-year-old woman with a transdiaphragmatic migrated gossypiboma following liver surgery.
Case Presentation: A-29 years old woman presented with dyspnea, abdominal pain, and fever, with imaging revealing a suspected hepatic abscess.
Introduction: Gangrenous cholecystitis is a serious complication of untreated gallbladder inflammation, necessitating immediate intervention. The primary resolution involves cholecystectomy, the surgical removal of the gallbladder.The Billroth II gastrectomy, named after Theodor Billroth, addresses gastric conditions by removing a portion of the stomach and reconnecting the remaining section to the small intestine.
View Article and Find Full Text PDFIntroduction: Splenic artery aneurysm (SAA) is a focal dilation of the splenic artery with varying etiologies including atherosclerosis, arteritis, or trauma. Giant SAAs with a diameter of 10 cm is rare and can lead to severe complications like rupture and fistulas. Therefore, an accurate and timely diagnosis and treatment are important.
View Article and Find Full Text PDFIntroduction: Extrahepatic bile duct injuries can occur after abdominal trauma, though more commonly they are iatrogenic. Definitive surgical repair is the mainstay of treatment but has a significant incidence of complications, particularly when managed by non-specialist surgeons or with delayed referral to a specialized center.
Case Presentation: A 17-year-old male presented with a blunt abdominal injury after a fall, resulting in a right hepatic duct injury that was managed with a Roux-en-Y hepaticojejunostomy.
Introduction: Richter's hernia is a relatively uncommon type of hernia that can lead to severe clinical consequences if left unaddressed. The definitive treatment involves the reduction and repair of the hernia defect, with various surgical approaches available, including open transabdominal, inguinal, obturator, and laparoscopic techniques, depending on the size of the defect and the viability of the involved bowel.
Case Presentation: A 29-year-old female patient presented with Richter's hernia, a rare type of hernia, and underwent surgical intervention to release the incarcerated bowel loop and resect the necrotic segment.
Critical mitral valve stenosis due to a failed bioprosthetic valve is associated with significant morbidity and mortality, with the transcatheter Valve-in-Valve (ViV) approach becoming a popular treatment option. We present a case of cardiogenic shock secondary to a stenotic mitral bio-prosthetic valve. The Heart team was consulted; the patient was a high-risk surgical candidate for valve replacement.
View Article and Find Full Text PDFIntroduction: Gossypiboma is a term used to describe a condition of leaving a surgical sponge or any other foreign object in a body cavity after surgery. Gossypiboma is a rare but serious medical and legal problem, as it may cause no symptoms or severe complications in the digestive system. In some cases, Gossypiboma may migrate through the wall of an organ and cause damage, such as perforation, obstruction, or fistula formation.
View Article and Find Full Text PDFSarcoidosis Vasc Diffuse Lung Dis
September 2023
Background And Aim: Cardiac sarcoidosis (CS) is the second most common cause of death in patients with sarcoidosis and data pertaining to its diagnosis and management is limited. We sought to describe diagnostic modalities and management of patients with CS in the United States, based on a national registry questionnaire.
Methods: We conducted a retrospective study based on a national registry investigating 3,835 respondents to the Foundation for Sarcoidosis Research Questionnaire.
It is common for patients with inferior myocardial infarction to experience right ventricular infarction, occurring in half of the patients with inferior myocardial infarction. Right ventricular failure due to acute right myocardial infarction is often associated with a worse prognosis. In this case, we report a patient with acute chest pain due to acute right coronary artery occlusion status post placement of multiple stents in the right coronary artery.
View Article and Find Full Text PDFProsthetic valve endocarditis is a devastating infection with a challenging diagnosis and management. Despite advances in its diagnostic modalities, medical, and surgical interventions, prosthetic valve endocarditis still carries high morbidity and mortality rates. Here, we report a case of prosthetic aortic valve endocarditis that progressed to involve the paravalvular space and the importance of multimodality cardiac imaging in the early detection of paravalvular complications.
View Article and Find Full Text PDFCOVID-19 is an established challenge to the health care professionals (HCPs) having physical, emotional, and psychological repercussions. We determine the perceptions of Pakistani HCPs regarding the risks and deaths related to COVID-19. A cross-sectional study was conducted among HCPs throughout Pakistan from 16th February 2021 to 6th March 2021 by disseminating an online Google questionnaire via all possible social media platforms including WhatsApp, Facebook, Twitter, and emails.
View Article and Find Full Text PDFBackground: Coronavirus disease-19 has a wide range of clinical presentations and varied outcomes. It is a new disease and researchers are trying to explore its clinical presentation and outcome to know more about the course of the disease. The objective of the present study was to determine the clinical and laboratory characteristics of Coronavirus disease-19 associated with severity of the disease.
View Article and Find Full Text PDFWe studied the clinical and epidemiologic features of an outbreak of Crimean-Congo hemorrhagic fever in Herat Province, Afghanistan. The study comprised 63 patients hospitalized in 2017. The overall case-fatality rate was 22.
View Article and Find Full Text PDFBackground: Burn scar treatment persists as an unsolved problem, involving thousands of affected patients disfigured for life.
Objectives: We sought to present our experience with the use of combined treatments for patients with burn scars.
Methods: This was a case series report of the senior author's experience during 8 years utilizing the combined treatments of Fraxel Restore (fractional laser) and microfat graft injection for 288 patients with burn scars.
Platelets are involved in hemostasis, inflammation, and thrombosis processes. Following a vascular damage, the endothelium releases protein factors, allowing the adhesion of subendothelium to platelets. Then platelets are activated, leading to the secretion of biologically-active ligands including thromboxane A2, adenosine diphosphate and serotonin.
View Article and Find Full Text PDFJ Ayub Med Coll Abbottabad
December 2017
Background: Patients with Rhegmatogenous retinal detachment develop raised intraocular pressure (IOP) when they undergo pars plana vitrectomy with silicone oil. The present study was done to document changes in IOP with silicone oil and after its removal.
Methods: The interventional study was conducted at Eye department of Lady Reading Hospital Peshawar, from August 2012 to July 2014 on 30 patients with Rhegmatogenous retinal detachment in whom pars plana vitrectomy with silicone oil injection was indicated.
Objective: To note ultrasonographic findings used for diagnosing plasma leakage in dengue haemorrhagic fever patients.
Methods: The observational retrospective study was conducted at the Holy Family Hospital, Rawalpindi and comprised records of patients with confirmed dengue infection who were screened for dengue haemorrhagic fever according to Dengue Expert Advisory Group criteria from July 1 to December 31, 2013. Each patient underwent ultrasonography for the detection of ascites, gall bladder wall thickness, pleural and/or pericardial effusion along with their quantification and localisation.