Effects of cigarette smoke condensate on reproduction in mice .

Smoking has dangerous and sometimes irreversible effects on various body tissues, including the reproductive system. We conducted this research to determine the effects of cigarette smoke condensate (CSC) on reproduction in mice. In this experimental study, 32 male and female NMRI mice were divided into four groups.

Effect of cigarette smoke condensate on mouse embryo development and expression of pluripotency and apoptotic genes .

The aim of the present study was to investigate the effect of cigarette smoke condensate (CSC) on development of mouse embryos. In total 3000 NMRI mice 2PN embryos were divided into six groups ( = 500). The test group was exposed to 20, 40, 80, 160 or 320 μg/ml of CSC.

A meta-analysis of the association of ApaI, BsmI, FokI, and TaqI polymorphisms in the vitamin D receptor gene with the risk of polycystic ovary syndrome in the Eastern Mediterranean Regional Office population.

Background: The results of case-control studies on the association between vitamin D receptor gene () polymorphisms and polycystic ovary syndrome (PCOS) are inconclusive.

Objective: We aimed to more precisely evaluate the correlation between the ApaI, BsmI, FokI, and TaqI gene polymorphisms and PCOS susceptibility.

Materials And Methods: PubMed, Scopus, Science Citation Index, and Google Scholar databases were searched to retrieve related reports released up to the end of 2020.

Serum levels of CTRP3 in diabetic nephropathy and its relationship with insulin resistance and kidney function.

Background: C1q TNF related protein 3 (CTRP3) is an adipokine secreted from adipose tissue. Previous studies have suggested that CTRP3 improves insulin sensitivity and reduces inflammation. Human studies have evaluated circulating levels of this adipokine in patients with diabetes mellitus (DM), diabetic retinopathy, metabolic syndrome, and coronary artery diseases.

The effect of the ovarian varicose vein on the DNA methylation in the rat's oocyte.

Objectives: We intended to determine whether the ovarian varicose which is one of the common etiologies of the pelvic congestion syndrome, has the ability to interfere with the DNA methylation reprogramming in the oocyte and thereby affect the oocyte quality or not.

Materials And Methods: Varicose model was induced according to the Turner's method in the rats. Briefly, a 20-gauge needle was placed on the left renal vein and a thread was tied over both the needle and the renal vein medial to the insertion of the ovarian vein, and then the needle was removed.

MicroRNAs-Based Imaging Techniques in Cancer Diagnosis and Therapy.

Cancer is one of the most serious global health concerns in different populations. Several studies indicated that there are many potentially promising cellular and molecular targets for cancer therapy within cancer cells and their microenvironment. Among different cellular and molecular targets involved in cancer pathogenesis, microRNAs (miRNAs) are well known as key targets for cancer therapy.