Publications by authors named "Mohammad J Hassan"

Intussusception is telescoping of a proximal segment of gastrointestinal tract within the lumen of another. Intussusception is a common presentation in pediatric population and present with a classic triad of abdominal pain, bloody diarrhea and a palpable mass. However, intussusception in adults is a rare entity accounting for only 5% of the total cases and is the underlying cause for 1%-5% of all the cases of intestinal obstruction.

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Objective: Primary Spindle cell tumors of the thyroid are very rare and comprise a myriad of differential diagnoses ranging from reactive proliferations to neoplastic processes. Differentiation amongst these rare entities is of utmost importance as it defines the prognosis and also guides future therapy.

Case Report: Hereby, we present a rare case of spindle cell variant of papillary thyroid carcinoma in a sixty-four-year-old female which posed a diagnostic challenge on histology.

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Development of a neoplasm in an ectopic breast is uncommon, while the development of phyllodes tumor in an ectopic breast in the axilla is even rarer. We report a rare case of a 51-year-old female who presented with a complain of swelling and pain in the right axilla with no associated complaints in other organs. Magnetic resonance imaging suggested a possibility of metastatic lymphadenopathy.

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 The objective of this study is to study the prevalence, clinical spectrum, and hematological profile of inherited bleeding disorder with special reference to von Willebrand disease in eastern India.  This prospective study was done in a tertiary care center in the eastern part of India over 2 years. Detailed history and clinical findings were noted in a proforma.

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Chlorazol yellow (CY) is a commonly used anionic, toxic, mutagenic, and potentially carcinogenic azo dye, which is menacing to the environment, aquatic system, food chain, and human health as well. To remove CY dye molecules from an aqueous medium, a series of Ce, Bi, and N co-doped TiO photocatalysts were prepared by varying the composition of the dopants. Under sunlight irradiation, the resultant 5 wt% (Ce-Bi-N) co-doped TiO composite catalyst was found to show the best catalytic activity.

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Malignant melanoma of the anorectal region is a very rare aggressive malignant neoplasm and it constitutes 1% of all malignant lesions of this area. About 70% of these lesions are pigmented, whereas 30% are amelanotic. Demonstration of immune markers of melanoma by immunohistochemistry (IHC) is required for confirming the diagnosis of amelanotic malignant melanoma.

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Background: The hallmark of tuberculosis in cytological smears is the presence of epithelioid cell granulomas, necrosis and AFB. In cases, where AFB not detected, diagnosis of tuberculosis can be made by ancillary tests like PCR which requires infrastructure besides being expensive. In India, where majority of population is rural-based there is an imminent need of some morphological change in cytological smears which can point towards diagnosis of tuberculosis in absence of AFB.

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Brenner tumors of ovary are usually an incidental finding. It is an uncommon tumor which is seen affecting women of fifth to sixth decade. It is classified under transitional cell tumors of ovary, which includes benign, borderline, and malignant Brenner tumors and transitional cell carcinoma.

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Article Synopsis
  • - The text discusses the rarity of breast tuberculosis (TB) in developing countries and its significance due to its potential to mimic breast cancer or present as an inflammatory mass.
  • - A retrospective study was conducted over two years, identifying eight cases of breast lesions linked to TB, with varying levels of granulomas and necrosis found in fine-needle aspiration cytology results.
  • - The conclusion emphasizes the need for healthcare professionals in India, a country where TB is common, to be aware of breast TB when evaluating breast masses, highlighting the importance of including it in differential diagnoses.
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Introduction: Gallbladder diseases are very common in Northern India, most common of which is Chronic Cholecystitis. Rarely, histopathological diagnosis of Eosinophilic Cholecystitis (EC) is given when transmural cellular infiltrate consists of more than 90% eosinophils.

Aim: To determine the prevalence and clinicopathological profile of eosinophilic cholecystitis at a tertiary care hospital of New Delhi.

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The thyroglossal duct cysts (TGDCs) are the most common congenital anomaly of the thyroid, usually manifested as painless midline neck mass. Malignancy is very rare and is reported in around 1% of cases as an incidental finding after histopathological evaluation of resected cyst. Papillary carcinoma is the most common carcinoma reported in TGDC.

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Atypical fibroxanthoma (AFX) is an uncommon spindle cell tumor with intermediate or borderline malignant potential. Clinically, it may be misdiagnosed as a squamous cell carcinoma (SCC) or malignant melanoma. Solar irradiation has been implicated in its pathogenesis.

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Squamous cell carcinoma (SCC) of the endometrium, whether primary or secondary to cervical cancer, is a rare entity. Primary endometrial squamous cell carcinoma in situ is even more uncommon; it usually occurs in postmenopausal women and has a strong association with pyometra. We report a 60-year-old multiparous postmenopausal woman who presented to the Hakeem Abdul Hameed Centenary Hospital, New Delhi, India, in May 2014 with a lower abdominal swelling corresponding in size to a pregnancy of 26 gestational weeks and vaginal discharge of one year's duration.

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Tuberculosis (TB) presenting as isolated liver mass without clinical evidence of TB is difficult to diagnose preoperatively and is usually mimicked by primary or metastatic carcinoma of the liver. Hepatic TB associated with carcinoma colon is a rare association which has very rarely been reported in the literature. This case illustrates the diagnostic difficulties of hepatic TB and the need to consider it in the differential diagnosis of hepatic nodular lesions in carcinoma colon patients.

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Tuberculous infection is highly prevalent in India, however, hydatid disease is relatively uncommon. Frequent sites of predilection of hydatid disease are the liver and lungs. Other unusual sites of infliction are the peritoneum, thyroid, breast, pancreas, and mediastinum.

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A hydroponics experiment was conducted to investigate the effect of salinity (NaCl) and cadmium (Cd) stresses on growth, lipid peroxidation, and antioxidant enzyme activities of three wheat cultivars differing in salt tolerance. Cd and NaCl stresses inhibited plant growth, reduced chlorophyll content, and increased melondialdehyde content and the activities of superoxide dismutase, catalase and peroxidase. The combined effect of NaCl and Cd on these parameters was larger than both NaCl and Cd alone.

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