Synthesis of benzo[]furo[2, 3-]phenazine derivatives through an efficient, rapid and via microwave irradiation under solvent-free conditions catalyzed by HPWO@FeO-ZnO for high-performance removal of methylene blue.

A rapid, one-pot synthesis of eight benzo[]furo[2,3-]phenazine derivatives has been achieved in moderate to good yields in good yields a multi-component of 2-hydroxynaphthalene-1,4-dione, arylglyoxal, indole (H, CH) in the presence of HPWO@FeO-ZnO magnetic core-shell nanoparticles (MCNPs) under solvent-free conditions using microwave irradiation. The catalyst was synthesised and characterised by X-ray diffraction, EDX, TEM, FESEM, TGA, VSM and atomic force microscope. As an application for the synthesised nanocatalyst, degradation of methylene blue as heavy-mass organic pollution was measured.

An Efficient, Green, Microwave-assisted Synthesis of Benzo[a]furo[2, 3-c]phenazine Derivatives with TiO-SOH as Cost-effective and Recyclable Catalyst under Solventfree Conditions.

Background: A rapid, efficient, and environmentally benign procedure for the synthesis of novel furo [2,3-c]phenazine derivatives has been developed via reactions of 2-hydroxynaphthalene-1,4-dione, arylglyoxals, and indole in the presence of TiO-SOH-catalyst (TSAC) as a recyclable heterogeneous catalyst under solventfree conditions using microwave irradiation.

Introduction: This study describes a successful approach for the synthesis of 2-(4-bromophenyl)-1-(1H-indol-3- yl) benzo[a]furo[2,3-c] phenazine in the presence of TiO-SOH-catalyst using microwave irradiation.

Objectives: In this paper, we report an efficient and convenient method for the synthesis of phenazine derivatives from benzo[a]phenazin-5-ol, arylglyoxal derivatives, and indoles in the presence of TiO-SOH-catalyst under microwave irradiation.

Preparation of four 1,4-dihydropyridine derivatives (DHPs) labeled with carbon-14.

The importance of DHPs compounds and the need for examining the mechanism of their effect, mandated us to synthesize a number of carbon-14 labeled 1,4-dihydropyridine derivatives for pharmacological studies. Simple preparation and suitable radiochemical yield were advantages of this preparation.

Benzofuran-derived benzylpyridinium bromides as potent acetylcholinesterase inhibitors.

A series of benzofuran-based N-benzylpyridinium derivatives 5a-o were designed and synthesized as novel AChE inhibitors. The synthetic pathway of the compounds involved the preparation of 4-(benzofuran-2-yl)pyridine intermediates via the reaction of different salicylaldehyde derivatives and 4-(bromomethyl)pyridine, followed by intramolecular cyclization. Subsequently, the 4-(benzofuran-2-yl)pyridines were N-benzylated by using appropriate benzyl bromide to afford the final product 5a-o.