Evaluation of Anti-inflammatory and Some Possible Mechanisms of Antinociceptive Effect of Ferula assa foetida Oleo Gum Resin.

Asafetida is well known for its medicinal and therapeutic values in Iranian folk medicine. This study was conducted to investigate the antinociceptive and anti-inflammatory effects of asafetida. In hot plate test, asafetida exhibited a significant antinociceptive effect at all administered doses and the most effective dose was 10 mg/kg.

Antinociceptive activity of Astragalus gummifer gum (gum tragacanth) through the adrenergic system: A in vivo study in mice.

Background: In Iranian traditional medicine, gum obtained from Astragalus gummifer and some other species of Astragalus was used as analgesic agent.

Objective: In this study, we investigated the antinociceptive effect of several concentrations (125, 250, and 500 μg/kg body weight) of Astragalus gummifer gum (AGG) on thermal and acetic acid induced pain in mice.

Materials And Methods: AGG was dissolved in distillated water and injected i.

Influence of asafoetida on prevention and treatment of memory impairment induced by d-galactose and NaNO2 in mice.

In Iranian traditional medicine, asafoetida is introduced as a valuable remedy for nervous disorders. Dementia was induced by injection of d-galactose and NaNO2 for 60 consecutive days. Animals were divided into normal control (NC), dementia control (DC), dementia prophylactic (DP), and dementia treated (DT).

Relaxant effect of Humulus lupulus extracts on isotonic rat's ileum contractions.

Objective: Many biological studies have been done to determine the activity of medicinal plants on gastrointestinal function. Since acetylcholine is the major transmitter involved in the gastrointestinal motility and there are some evidences regarding the cholinergic modulatory effect of hops extract, in the present study spasmolytic and antispasmodic action of hops (Humulus lupulus) on acetylcholine-induced contraction in isolated rat's ileum was evaluated.

Material And Methods: In this study, pieces of isolated rat's ileum were mounted in the internal chamber of an organ bath which was filled with Tyrode's solution and tightly tied to the lever of an isotonic transducer.

The effect of Carum Copticum extract on acetylcholine induced contraction in isolated rat's ileum.

Aims: There are many biological investigations for determining an effective cure for the dysfunction of gastrointestinal tracts, using herbal medicine. It has been reported that Carum Copticum is a bactericidal agent and possesses anticholinergic, antihistaminic and b-adrenergic stimulatory effects in some tissues. However, these effects of Carum Copticum on mechanical activities of isolated intestine are not clearly identified yet.