Lentinan and β-glucan extract from shiitake mushroom, , alleviate acute LPS-induced hematological changes in mice.

Objectives: Immunomodulatory activity of β-glucans of shiitake mushroom () has been known. We investigated whether β-glucans from would attenuate the acute effects of lipopolysaccharides (LPS) on peripheral hematological parameters in mice.

Materials And Methods: An in-house β-glucans extract (BG) prepared from fruiting bodies of shiitake mushroom was chemically measured and characterized using spectrophotometry and HPLC.