Publications by authors named "Mohammad Hasan Moshafi"

Background: Persian Medicine is one of the oldest and richest complementary and alternative options in the field of medicine and has a comprehensive medical system. Henna oil is recommended in Persian Medicine for the treatment of numerous women's diseases such as cervicitis. To date, henna has been used for many medical purposes, including astringent, bleeding, cardioinhibitory, hypotension, and relaxation.

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Purpose: In this study, for the first time, new nanoparticles of La/α-AlO were synthesized with the ultrasonic-assisted hydrothermal method in the presence of honey as an eco-friendly and natural reagent.

Methods: The as-synthesized La/α-AlO nanoparticles were characterized using scanning electron microscopy (SEM), transition electron microscopy (TEM), X-ray diffraction spectroscopy (XRD), energy dispersive X-ray (EDX), UV-visible spectroscopy, and Fourier transform infrared spectroscopy (FTIR) techniques. In this work, we report optimum conditions to synthesize La/α-AlO nanoparticles as novel material and as a candidate for antibacterial activity in antibacterial drugs.

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Biotemplates are attractive templates for the synthesis of nanometals and inorganic compound nanostructures. In this work, for the first time, iron oxide quantum dot nanoparticles (QDNPs) were prepared using albumen as a biotemplate. Next, the prepared nanoparticles were characterized using dynamic light scattering for determination and evaluation of the hydrodynamic diameter and zeta potential of the particles.

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During screening for antibiotic producing microorganisms from environmental soil samples, the supernatant of a bacterial isolate was found to have antibacterial and antifungal activity on the standard indicator species. The standard cylinder-plate method was used to determine the inhibitory effect of the crude supernatant of each isolate on 6 bacterial and 3 fungal standard strains by measuring the diameter of inhibition zone. The highest inhibition zone on Aspergillus niger belonged to culture broth of isolate FAS1 by 25 mm, and this isolate was the most efficient microorganism to inhibit standard bacterial and fungal species.

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Two series of 2-(5-nitro-2-furyl)- and 2-(1-methyl-5-nitro-1H-imidazol-2-yl)-5-propyl, allyl and propargyl)thio-1,3,4-thiadiazoles (6a-f) and 2-(5-nitro-2-furyl)- and 2-(1-methyl-5-nitro-1H-imidazol-2-yl)-5-(nitrobenzyl)thio-1,3,4-thiadiazole derivatives (8a-f) have been synthesized and evaluated against Mycobacterium tuberculosis, as part of the TAACF TB screening program under direction of the US National Institute of Health, the NIAID division. Primary screening was conducted at a single concentration, 6.25 microg mL(-1), against M.

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A series of N-[5-(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazole-2-yl] and N-[5-(nitrophenyl)-1,3,4-thiadiazole-2-yl] piperazinyl quinolone derivatives (5a-c and 5d-l) were synthesized and evaluated for in vitro antibacterial activity against some Gram-positive and Gram-negative bacteria. The antibacterial data revealed that all nitroimidazole derivatives (5a-c) showed interesting activity against tested Gram-positive bacteria (minimum inhibitory concentration, MIC=0.008-0.

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