Transepithelial Versus Epithelium-off Photorefractive Keratectomy in High Compound Myopic Astigmatism: A Contralateral Eye Study.

Purpose: To compare clinical outcomes of transepithelial photorefractive keratectomy (t-PRK) and conventional epithelium-off PRK (PRK) in patients with high compound myopic astigmatism.

Methods: Sixty eyes of 30 myopic individuals with at least -2.50 diopters (D) of spherical equivalent and 3.

Posterior Pseudo-Lenticonus Sign in a Patient with Nipple Cone Keratoconus.

Purpose: To describe a previously unreported posterior pseudo-lenticonus sign in a patient with nipple cone keratoconus (KC).

Case Report: A 32-year-old female presented with complaints of right eye visual acuity loss. Although she was initially diagnosed with posterior lenticonus, the additional clinical evaluation revealed no true lenticonus.

Customized Stromal Lenticule Implantation for Keratoconus.

Purpose: To investigate the potential benefit of keratoconus surgery using customized corneal stromal donor lenticules obtained from myopic small incision lenticule extraction (SMILE) surgery by femtosecond laser.

Methods: In this prospective, consecutive, non-comparative series of cases, 22 lenticules were obtained from 22 myopic patients who had SMILE with a lenticule central thickness of greater than 110 µm. The lenticules were implanted in 22 eyes with advanced keratoconus.

Comparison of Toric Implantable Collamer Lens and Toric Artiflex Phakic IOLs in Terms of Visual Outcome: a Paired Contralateral Eye Study.

Purpose: This study sought to compare the postoperative visual outcomes of toric implantable collamer lens (T-ICL) with toric Artiflex (T-Artiflex) lenses.

Design: Alternating treatment, contralateral eye matched clinical study.

Methods: This study compared 82 eyes of 41 patients with T-ICL lenses in one eye and toric Artiflex implantation in the contralateral eye to correct myopic astigmatism.

Comparison of densitometric profile after deep lamellar keratoplasty with two different techniques for treatment of keratoconus.

Purpose: To compare densitometric outcome of two techniques of deep lamellar keratoplasty using Pentacam HR corneal densitometry software.

Methods: Postoperative outcomes of 31 patients with big bubble (BB) and 28 patients with Melles (M) surgery for the treatment of keratoconus were evaluated. Data were gathered at least 3 months after the removal of all sutures including demographic data, uncorrected distance visual acuity (UCDVA), best spectacle-corrected visual acuity (BSCVA), refraction and endothelial cell count.

Topography-guided transepithelial photorefractive keratectomy to correct irregular refractive errors after radial keratotomy.

Purpose: To evaluate the efficacy and safety of topography-guided transepithelial photorefractive keratectomy (PRK) in a group of patients with post-radial keratotomy (RK) showing irregular corneas.

Setting: Feiz University Hospital, Isfahan, Iran.

Design: Prospective case series.

A model for predicting sulcus-to-sulcus diameter in posterior chamber phakic intraocular lens candidates: correlation between ocular biometric parameters.

Purpose: The aim of this study was to determine the correlation between ocular biometric parameters and sulcus-to-sulcus (STS) diameter.

Methods: This was a cross-sectional study of preoperative ocular biometry data of patients who were candidates for phakic intraocular lens (IOL) surgery. Subjects underwent ocular biometry analysis, including refraction error evaluation using an autorefractor and Orbscan topography for white-to-white (WTW) corneal diameter and measurement.

Comparative analysis of the visual performance after implantation of the toric implantable collamer lens in stable keratoconus: a 4-year follow-up after sequential procedure (CXL+TICL implantation).

Aims: To report on 4-year postoperative visual performance with the toric implantable collamer lens (TICL) for stable keratoconus after sequential procedure (corneal collagen crosslinking plus TICL implantation).

Methods: Forty eyes of 24 patients with stable keratoconus with myopia between 0.00 and -18.

Comparison of Sub-Bowman Keratoplasty Laser Keratomileusis Flap Properties between Microkeratome and Femtosecond Laser.

Background: Since thin and high-quality flaps produce more satisfactory surgical outcomes, flaps created by mechanical microkeratomes are more economical as compared with femtosecond lasers, and no Iranian study has concentrated laser keratomileusis (LASIK) flap peculiarities between Moria Sub-Bowman keratoplasty (SBK) microkeratomes and LDV femtoseconds, the present study compares and contrasts them.

Materials And Methods: This cross-sectional study was done on all patients who underwent LASIK surgery 1-month before this study. Thirty eyes were divided into per group.

Toric Intraocular Lens for Astigmatism Correction in Cataract Patients.

Background: To assess the clinical consequences of AcrySof toric intraocular lens (IOL) and Hoya toric IOL implantation to correct preexisting corneal astigmatism in patients undergoing cataract surgery.

Materials And Methods: In this study, we examined 55 eyes of 45 patients with at least 1.00 D corneal astigmatism who were scheduled for cataract surgery.

Comparing aspheric ablation profile with standard corneal ablation for correction of myopia and myopic astigmatism, a contralateral eye study.

The purpose of this study is to compare visual outcomes of myopic refractive surgery, using tissue saving (TS), a standard ablation profile by a Technolas 217z100, and aberration smart ablation (ASA), an aspheric algorithm by a MEL 80 excimer laser in two eyes of one patient. In this prospective interventional paired-eye controlled study, a total of 100 eyes of 50 participants with myopia with or without astigmatism underwent thin-flap Femto-LASIK, using a Femto LDV femtosecond laser (Ziemer Ophthalmic Systems AG, Port, Switzerland). For each patient, one eye was randomly treated with tissue-saving algorithm (TS group) by the Technolas 217z100 excimer laser and the other eye was treated with optimized smart ablation profile (ASA group) by the MEL 80 excimer laser.

Photorefractive keratectomy in the management of postradial keratotomy hyperopia and astigmatism.

Background: The aim of this study is to evaluate the results of photorefractive keratectomy (PRK) in the management of postoperative hyperopia and astigmatism in patients with history of radial keratotomy (RK).

Materials And Methods: This prospective nonrandomized noncomparative interventional case series enrolled consecutive eyes treated with PRK after RK. In cases, in which (1) wavefront (WF) scan was undetectable during primary examinations; and/or, (2) WF data were not transferable to the excimer laser device, patients were treated with the tissue-saving (TS) mode.

Effect of iris registration on outcomes of FEMTOLASIK for myopia and myopic astigmatism.

Purpose: To compare the visual and refractive outcomes after FEMTOLASIK with and without iris registration.

Methods: In this randomized, prospective, comparative, contralateral eye study, 118 eyes of 59 patients with myopia and myopic astigmatism underwent LASIK using the Femto LDV femtosecond laser (160 µm) and the MEL80 with or without iris registration. For each patient, iris registration FEMTOLASIK was performed on one eye and non-iris registration FEMTOLASIK was performed on the other eye, assigned at random.

Photorefractive keratectomy for patients with preoperative low Schirmer test value.

Purpose: To compare dry eye signs and symptoms between patients with preoperative low and normal Schirmer test after Photorefractive keratectomy (PRK).

Methods: In this prospective, nonrandomized, comparative case series, 76 eyes of 76 patients were preoperatively categorized into two groups according to selected criteria for characterization of tear film status: the low Schirmer test value (STV) group and the normal STV group. For the tear function assessment, we performed a Schirmer test with and without anesthesia, tear break-up time (TBUT) test, and measurement dry eye symptoms using the Farsi translation of Ocular Surface Disease Index (OSDI) questionnaire pre- and 3 months post-operation.

Evaluation of corneal higher order aberrations in normal topographic patterns.

Purpose: This study reports the characteristics of corneal higher order aberrations (HOAs) in eyes with normal topographic pattern using the Pentacam scheimpflug system.

Methods: In this prospective, observational, comparative study, 165 eyes of 97 patients separated into five groups based on corneal topographic patterns were enrolled. All eyes received a comprehensive ophthalmologic examination including corneal tomographic analysis with the Pentacam system.

Evaluation of the outcomes of corneal collagen cross-linking in progressive keratoconic eyes.

Background: Corneal collagen cross-linking (CXL) is gaining popularity as a treatment in arresting the progression of keratoconus. It is a relatively new therapy using ultraviolet-A (UVA) with a photosensitizer to increase corneal stiffness. The purpose of this study was to evaluate visual, keratometric and topographic outcomes after corneal CXL in progressive keratoconic eyes.

Evaluation of corneal thickness alterations during menstrual cycle in productive age women.

Purpose: To determine the change in corneal thickness through different phases of menstrual cycle in women who are in their productive age.

Materials And Methods: Fifty healthy women with normal past medical history were enrolled in this prospective study. Central corneal thickness was measured with ultrasound pachymeter three times during a menstrual cycle: Beginning of the cycle (days 1-3), ovulation time, and at the end of cycle (days 27-32).

Refractive and Aberration Outcomes after Customized Photorefractive Keratectomy in Comparison with Customized Femtosecond Laser.

To compare the refractive and visual outcomes and higher order aberrations in patients with low to moderate myopia who underwent customized photorefractive keratectomy (PRK) or femtosecond laser in situ keratomileusis (Femto-LASIK) this research performed. This study includes data of 120 consecutive eyes of 60 patients with myopia between -3.00 D and -7.

Flexible toric iris claw phakic intraocular lens implantation for myopia and astigmatism.

Purpose: To assess the visual and refractive outcomes of flexible toric iris claw phakic intraocular lens implantation for correction of moderate to high myopia with astigmatism.

Methods: In this non-randomized prospective study, 31 eyes of 18 patients including 8 male and 10 female subjects with mean age of 27.62±5.

Visual outcomes of Femto-LASIK for correction of residual refractive error after corneal graft.

Purpose: To evaluate the outcomes of the Femto-LASIK method in the treatment of refractive errors following penetrating keratoplasty (PK) at the Persian Eye Clinic, Isfahan, Iran

Methods: In a prospective, non-comparative case series, 34 consecutive symptomatic eyes of 34 patients after corneal graft, were operated on. Tissue-saving (TS) Femto-LASIK (n = 16), and Zyoptix Personalized Treatment Advanced (PTA) Femto-LASIK (n = 18) were performed using the Bausch & Lomb Technolas 217z excimer laser and Zyoptic algorithm. Uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), manifest refraction, contrast sensitivity, and HOAs were evaluated preoperatively and 12 months after enhancement treatment.

Visual outcomes of topography-guided excimer laser surgery for treatment of patients with irregular astigmatism.

The aim of this study was to evaluate the efficacy, safety, and predictability of topography-guided treatments to enhance refractive status following other corneal surgical procedures. In a prospective case series study, 28 consecutive eyes of 26 patients with irregular astigmatism after radial keratotomy, corneal transplant, small hyperopic and myopic excimer laser optical zones, and corneal scars were operated. Laser-assisted in situ keratomileusis (LASIK) (n = 8) and photorefractive keratectomy (PRK) (n = 20) were performed using the ALLEGRETTO WAVE excimer laser and topography-guided customized ablation treatment software.

Artiflex versus STAAR implantable contact lenses for correction of high myopia.

Purpose: To compare two phakic intraocular lenses, Artiflex and STAAR(®) implantable contact lens (ICL), in high myopia.

Setting: Isfahan Ophthalmology Clinic, Iran.

Materials And Methods: In a randomized, prospective clinical trial study, 40 eyes of 20 patients who came to Isfahan ophthalmology clinic to correct their refractive error were examined.

Alcohol-assisted versus Mechanical Epithelium Removal in Photorefractive Keratectomy.

Purpose: To compare the outcomes and complications of alcohol-assisted versus mechanical corneal epithelial debridement for photorefractive keratectomy (PRK).

Methods: This randomized controlled trial included 1,250 eyes of 625 patients undergoing PRK for correction of myopia and myopic astigmatism. Each patient was randomly assigned to alcohol-assisted or mechanical epithelial removal.

Outcomes of photorefractive keratectomy with intraoperative mitomycin-C.

Purpose: To report the efficacy, safety, predictability and complications of photorefractive keratectomy (PRK) with intraoperative application of mitomycin-C (MMC).

Methods: This historical cohort study was performed on 1,250 eyes of 625 patients who underwent PRK using the Technolas 217 excimer laser machine by a single surgeon with intraoperative use of MMC 0.02% up to 2 minutes, depending on depth of ablation.