Novel parallel inputs shift registers with terminals in nanotechnology.

This paper was focused on logic gates, D-latch, parallel-parallel shift-registers, and parallel-series shift registers, which are used as basic circuits in numerous circuits as well as computational and comparative units. To design proposed shift registers, D-latch which is the vital gate, is designed carefully for minimum size, decreasing number of cells and good performance for delay. The proposed level-sensitive parallel-in parallel-out () shift registers with reset terminal and with both set and reset terminals (single-layer and multi-layer), edge-sensitive shift registers with reset and set/reset abilities (single-layer and multi-layer), and the parallel-in serial-out () shift registers were designed using the proposed D-latches.

New tile-based circuits converting BCD code to gray, excess-3, and aiken codes in quantum-dot cellular automata (QCA) nanotechnology.

The development of new methods and technologies for improving the stability and reducing the power consumption of electronic devices is a crucial area of research. Quantum-dot Cellular Automata (QCA) has emerged as a promising alternative to the traditional Complementary Metal-Oxide-Semiconductor (CMOS) technology, offering superior optimization in terms of physical size and energy efficiency. This paper introduces three novel digital code converters, designed using the tile-based approach to simplify circuit implementation and enhance integration through optimized majority and inverter gate structures.

Mendelian Susceptibility to Mycobacterial Disease with Signal Peptide Peptidase-like 2A (SPPL2A) Deficiency: A Case Report.

Mendelian susceptibility to mycobacterial disease (MSMD) is a rare genetic disorder characterized by immunodeficiency, leading to increased susceptibility to mycobacterial infections. Studies have identified several genes that are associated with MSMD in the interferon-gamma/interleukin (IL)-12/IL-23 signaling pathway. One of these genes is signal peptide peptidase-like 2A (SPPL2A), which is very rare, and defects in this gene have been reported only in 3 patients with MSMD.

Risk Factors and Comorbidities of Recurrent Nasal Polyposis.

Chronic rhinosinusitis is divided into two groups, which are Chronic rhinosinusitis with nasal polyps (CRSwNP) and without nasal polyps (CRSsNP). The rate of post-surgical recurrence in the CRSwNP is high, and predicting factors are unknown. This study aims to identify and evaluate risk factors associated with treatment-resistant and recurrent CRSwNP.

Pseudo random bit generator in QCA for high speed communications.

Quantum-dot cellular automata (QCA) technology is another new technology in the field of nanoelectronics and quantum. With the help of this technology, basic to advanced digital circuits can be designed and implemented with low energy consumption and small area. Therefore, in this paper, a new design for a four- and eight-bit Linear feedback shift register (LFSR) or random counter, as well as a rising-edge-sensitive D flip-flop with the least possible number of cells and the smallest area, was presented.

Reducing health disparities in providing care services in the intensive care unit: a critical ethnographic study.

Objective: The intensive care unit, with its structural complexity and the exposure of critically ill patients to various disparities, presents a significant setting for health disparities. This critical ethnographic study sought to uncover cultural knowledge and ethical practices for reducing health disparities in providing care services within the intensive care unit. The focus was on understanding how ethical considerations and cultural competence can address and mitigate these disparities effectively.

Health disparities in service delivery in the intensive care unit: A critical ethnographic study.

Background: The intensive care unit has structural complexities, and critically ill patients are exposed to disparities. Thus, the intensive care unit can be a potential health disparity setting.

Aim: This study explored cultural knowledge associated with health disparities in the intensive care unit.

Laser-induced tuning of crystallization in tetracene thin films.

This study explores how laser light affects the morphology of tetracene films, and it presents novel strategies for improving the creation of thin films used in (opto-)electronic devices. We demonstrate that laser light (532 nm, 1.1 W mm), applied during tetracene deposition, not only increases grain size but also induces photoalignment.

A complicated case of primary aortojejunal fistula: A case report.

Background: Aortoenteric fistulas are rare and life-threatening pathology characterized by an abnormal connection between the aorta and the gastrointestinal tract.

Case Presentation: The patient is a 61-year-old male who initially presented with hypogastric pain, hematemesis, and melena. Computed tomography angiography (CTA) revealed an abdominal aorta aneurysm but not a fistula.

Ageism and lookism as stereotypes of health disparity in intensive care units in Iran: a critical ethnography.

Background: The intensive care unit presents structural complexities, and the prevailing power imbalance between patients and staff can lead to health disparities. Hence, unveiling the underlying factors that give rise to and reinforce these disparities can contribute to their prevention. This study aims to shed light on the stereotypes linked to ageism and lookism, which perpetuate health disparities within the intensive care unit setting in Iran.

Expression of Heat Shock Protein 70 (HSP70) and Astacin Genes of as well as HSP70 and HSP17.1 Genes of in Adult and Larval Stages of .

Background: Uncovering the roles and characteristics of pathogenesis-related molecules can help us develop novel management methods in parasitology. In this study, we studied the expression levels of heat shock protein70 (HSP70) () and astacin () as pathogenesis-related genes as well as the expression of HSP70 and HSP17.1 (, ) in the larvae and adult stages of .

Evaluating the effects of Bacopa monnieri on cognitive performance and sleep quality of patients with mild cognitive impairment: A triple-blinded, randomized, placebo-controlled trial.

Introduction: Mild cognitive impairment is the middle level of natural cognitive impairment during primary steps of dementia. There are a few studies about improving the cognitive performance and sleep quality in patients with a limited dementia. So, this study was conducted to evaluate the effects of Bacopa monnieri on cognitive performance and sleep quality of patients with mild cognitive impairment.

New amide and diterpene alkaloids with anticholinesterase activity from Delphinium cyphoplectrum roots.

Background: The cholinergic hypothesis posits a robust correlation between the onset of Alzheimer's disease and a pronounced deficit in acetylcholine, a pivotal neurotransmitter crucial for the central cholinergic nervous system's function, pivotal for memory and learning. Diterpene alkaloids exhibit intricate and distinctive chemical structures that facilitate their passage through the blood-brain barrier. Moreover, their potent pharmacological attributes render them promising candidates for addressing central nervous system disorders.

Mesenchymal Stem Cell-derived Exosome; An Interesting Nanocarrier to Improve Allergen-specific Intranasal Immunotherapy.

Increasing the efficacy of allergen-specific intranasal immunotherapy (INIT) has recently been the main goal of several studies to establish this route as a safe delivery method through mucosal pathways. In this case, the present study evaluated the potential of INIT using ovalbumin (OVA)-loaded mesenchymal stromal/stem cell (MSC)-derived exosomes (Exo-OVA) in an allergic asthma mouse model. Together with control groups, sensitized Balb/c mice underwent intranasal immunotherapy with Exo-OVA (10 μg OVA per dose) for three consecutive weeks.

Novel level and edge-triggered universal shift registers with low latency in QCA technology.

Shift registers are one of the main blocks in processors. In this paper, two new universal shift registers are designed based on Quantum-Dot Cellular Automata (QCA) nanotechnology. Both of the proposed level triggered and edge triggered universal shift register in QCA technology shows good performance in regards of the number of cells, occupied area, delay, and power.

The potential immunomodulatory effect of levamisole in humans and farm animals.

This study conducted a literature review to investigate the immunomodulatory effect of levamisole in both humans and farm animals. The following procedure was followed for database searching: PubMed, Google Scholar, Web of Science, and Cochrane Library. All research works were updated to September 2022.

The effects of Fasciola hepatica recombinant proteins (peroxiredoxin and cathepsin L1) on Crohn's disease experimental model.

The immunomodulatory potential of the excretory-secretory (E/S) proteins of the helminths has been shown in previous investigations. This study evaluated the effects of the recombinants and excretory-secretory proteins of the Fasciola hepatica on induced colitis in Balb/c mice. The F.

Tic disorder in allergic rhinitis children and adolescents: a case-control study.

Background: Allergic rhinitis is the most common allergic disease. It can accompany psychological disorders such as tic disorders due to the prolonged course of the symptoms of allergic rhinitis. This pioneer case-control study aims to investigate tic disorders in children and adolescents under 18 years of age diagnosed with allergic rhinitis.

A decreased level of high-density lipoprotein is a possible risk factor for type 2 diabetes mellitus: A review.

Introduction: Type 2 diabetes mellitus (T2DM) is characterized primarily by dyslipidemia and hyperglycemia due to insulin resistance. High-density lipoprotein (HDL) play a significant role in preventing the incidence of dyslipidemia and its complications. HDL has different protective functions, such as reducing oxidation, vascular inflammation, and thrombosis; additionally, its anti-diabetic role is one of the most significant recent discoveries about HDL and some of its constituent lipoproteins.

Comparison of RT-LAMP and RT-qPCR assays for detecting SARS-CoV-2 in the extracted RNA and direct swab samples.

Rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in infected patients is critical for infection control. Loop-mediated isothermal amplification (LAMP) has been demonstrated to be a rapid, simple, reliable, cost-effective and sensitive method to detect SARS-CoV-2 in a variety of samples in considerably less time than Real-Time PCR. In this study, we developed and optimized a rapid detection method for SARS-CoV-2 based on RT-LAMP method utilizing a specific primer set targeting the ORF1a gene and then examined its sensitivity and efficiency using a serially diluted viral RNA sample with a known concentration.

Synthesis of Chiral Triazine Frameworks for Enantiodiscrimination.

Manipulation of the structure of covalent organic frameworks at the molecular level is an efficient strategy to shift their biological, physicochemical, optical, and electrical properties in the desired windows. In this work, we report on a new method to construct chiral triazine frameworks using metal-driven polymerization for enantiodiscrimination. The nucleophilic substitution reaction between melamine and cyanuric chloride was performed in the presence of PdCl, ZnCl, and CuCl as chirality-directing agents.

Predictors of emotional intelligence among family caregivers of cancer patients: A cross-sectional study.

Background: Family caregivers of cancer patients must have strong emotional intelligence skills essential for understanding one's and others' feelings and learning how to cope.

Objectives: The present study aims to determine the predictive factors of emotional intelligence and its relationship with spiritual intelligence, coping, and knowledge and experience about pain among family caregivers of cancer patients in Iran.

Methods: A cross-sectional, descriptive study was conducted in 2020-2021.

Novel combination therapy for respiratory diseases of small ruminants: Field studies of over 10 years.

Objective: This study aimed to evaluate a new drug combination for small ruminant respiratory diseases to find a better treatment protocol for the potential replacement of older methods.

Materials And Methods: A total of 6,886 animals received common respiratory disease therapies out of 15,845 animals that had respiratory disorders. The new combination therapy technique treated the remaining animals (8,968).

The effect of rosemary hydroalcoholic extract on cognitive function and activities of daily living of patients with chronic obstructive pulmonary disease (COPD): A clinical trial.

Background: In patients living with chronic obstructive pulmonary disease (COPD), cognitive impairment and reduced activities of daily living (ADLs) are associated with poor clinical outcomes.

Aim: The aim of the present study was to determine the effect of rosemary hydroalcoholic extract on cognitive function and ADLs in patients with COPD.

Methods: A total of 77 COPD patients aged 40-80 years were assigned to two intervention and control groups by random stratified block method in the current tripleblind clinical trial.

Effect of melatonin on steroidogenesis-related enzymes expression and testosterone synthesis following CoCl-induced hypoxia in TM3 Leydig cells.

Objectives: This study examined the effects of melatonin treatment on steroidogenesis dysfunction and testosterone impairment, following CoCl-induced hypoxia in TM3 Leydig cells.

Materials And Methods: The TM3 cells were divided into four groups. The first group received no treatment.