Paradoxical brain herniation following decompressive craniectomy: A case series and systematic review of literature.

Introduction: Paradoxical brain herniation (PBH) represents a rare and potentially life-threatening complication observed in individuals following decompressive craniectomy. Its diagnosis necessitates a high level of suspicion, combined with clinical and imaging evidence, such as midline shift, herniation, and a decreased Glasgow Coma Scale (GCS). Given the rarity and severity of this condition, we conduct a comprehensive literature review to identify all documented predisposing factors, clinical presentations, and appropriate clinical management.

The Effect of Garlic (Allium Sativum) on Polycystic Ovary Syndrome Related Hormones and Glycemic Parameters: A Randomized, Double-Blinded Clinical Trial.

Background: The purpose of the present study was to investigate the effect of garlic supplementation on androgen levels and glycemic-related markers in patients with PCOS.

Methods: In these 8 weeks of randomized double-blinded control trial, 80 women were randomly assigned into two groups in which patients were asked to intake either 800 mg/day garlic or an identical placebo. A blood sample was obtained pre- and post-trial to assess androgens and glycemic-related parapets.

The Therapeutic Impact of Garlic (Allium Sativum) on Oxidative Stress Markers among Polycystic Ovary Syndrome Patients: A Randomized, Double-Blinded Clinical Trial.

Background: The present study aimed to investigate the effect of garlic supplementation on oxidative stress markers in patients with polycystic ovary syndrome (PCOS).

Methods: Eighty patients with PCOS were randomized and instructed to consume either garlic supplementation (800 mg/day) or a placebo (starch) for 8 weeks. They were also asked to avoid intake of any other supplement during the study.

The effect of garlic (Allium sativum) supplementation on the lipid parameters and blood pressure levels in women with polycystic ovary syndrome: A randomized controlled trial.

Polycystic ovary syndrome (PCOS) is the most prevalent female endocrine-related disorder in reproductive ages. The aim of the study was to investigate the effect of garlic on the lipid parameters and blood pressure levels in women with PCOS. The present study was a randomized, double-blinded control trial, conducted on 80 PCOS patients.

Omega-3 and vitamin E co-supplementation can improve antioxidant markers in obese/overweight women with polycystic ovary syndrome.

Polycystic ovary syndrome is one of the most important factors in female infertility. Oxidative stress is likely to contribute to increased insulin and androgen production in the ovaries, as well as probably impairing follicle production. This study aims to determine the complementary effects of omega-3 and vitamin E supplements on certain oxidative stress indices in obese and overweight women with polycystic ovary syndrome.

Association of E-selectin with hematological, hormonal levels and plasma proteins in children with end stage renal disease.

Background: Hypercoagulable state is a common serious problem in patients with end-stage renal disease (ESRD). ESRD patients are in a condition of chronic inflammation. An increased level of E-selectin, "a key adhesion molecule that regulates leukocyte bindings to endothelium at damaged sites," accompanies the higher risk of inflammation in ESRD patients.

Effects of Vitamin E on seizure frequency, electroencephalogram findings, and oxidative stress status of refractory epileptic patients.

Background: Oxidative stress has been a frequent finding in epileptic patients receiving antiepileptic drugs (AEDs). In this study, the influence of Vitamin E on the antiseizure activity and redox state of patients treated with carbamazepine, sodium valproate, and levetiracetam has been investigated.

Materials And Methods: This double-blind, placebo-controlled trial was carried out on 65 epileptic patients with chronic antiepileptic intake.

Assessing of plasma levels of iron, zinc and copper in Iranian Parkinson's disease.

Background: Trace elements have long been suspected to be involved in Parkinson's disease (PD) pathogenesis, but their exact roles have been remained controversial. In this study, we assessed the levels of copper (Cu), iron (Fe) and zinc (Zn) in different stage of PD patients.

Materials And Methods: Serum concentrations of iron, copper and zinc were measured in 109 patients with PD by colorimetric methods.

Effect of taking dietary supplement on hematological and biochemical parameters in male bodybuilders an equation model.

Background: The improved physical action following administration of supplements to bodybuilders was supported by changes in laboratory parameters. Despite the fact that these supplements are sometimes associated both advantage and side effects, this study were conducted for the purpose of evaluating the possible effects of some commonly used supplements in bodybuilders on the hematological and biochemical parameters.

Materials And Methods: In this study, we included 40 male bodybuilders as cases and 40 controls in the age group of 20-40 years.

Rare Case of Rapidly Worsening REM Sleep Induced Bradycardia.

Sinoatrial arrest also known as sinus pause occurs when sinoatrial node of the heart transiently ceases to generate the electrical impulse necessary for the myocardium to contract. It may last from 2.0 seconds to several minutes.

Atrial Fibrillation and Colonic Neoplasia in African Americans.

Background: Colorectal cancer (CRC) and atrial fibrillation/flutter (AF) share several risk factors including increasing age and obesity. However, the association between CRC and AF has not been thoroughly examined, especially in African Americans. In this study we aimed to assess the prevalence of AF and its risk factors in colorectal neoplasia in an African American.

Bone turnover markers in epileptic patients under chronic valproate therapy.

Background: The effects of chronic valproic acid administration on bone health have been a matter of concern and controversy. In this study, the bone status following valproate intake was assessed by using several bone-related biochemical markers.

Materials And Methods: In this case-control study, 62 epileptic patients and 40 age- and gender-matched controls were enrolled.

Association between serum biochemical levels, related to bone metabolism and Parkinson's disease.

Background: Vitamin D insufficiency and serum calcium disturbance have been reported to be more common in Parkinson's disease (PD) patients than in healthy control subjects, which may be due to a chronic disease or reduced mobility contributes to these relatively disturbances. Because of the high-vitamin D insufficiency in our population, we aimed to compare a biochemical levels which are related to bone metabolism, in PD patients in comparison with age-matched healthy controls, for the 1(st) time in a Middle East population.

Materials And Methods: This case-control study was involved 105 (20 were excluded) PD patients, who were age- and -sex matched with 112 controls.

Is anti-cyclic citrullinated Peptide antibody a good value biomarker for Alzheimer disease?

Background: Alzheimer's disease (AD) is one of the most important neurodegenerative disorder. Anti-cyclic citrullinated peptide (anti-CCP) may all be involved in the development of vascular disease such as AD. The aim of this study is detection of seropositivity for anti-CCP antibody in AD patients.

Spontaneous coronary artery dissection: aggressive vs. conservative therapy.

Background: Spontaneous coronary artery dissection (SCAD) is a rare condition that commonly presents as an acute coronary event in the younger population, especially in females of childbearing age. Generally, there is no consensus on the etiology, prognosis, and treatment of SCAD.

Methods: The Medline database was searched for "spontaneous coronary artery dissection" between 1931 and 2008.

Ineffectiveness of folic acid supplementation against phenytoin-induced decrease in salivary immunoglobulin A concentration of epileptic patients.

Aims: This study was designed to investigate if folate treatment is able to reverse the phenytoin-induced deficiency of salivary immunoglobulin A (IgA).

Methods And Material: Twenty-five epileptic patients who had been under phenytoin therapy for at least the last 6 months were randomly selected and subjected to folic acid supplementation, 1 mg/day. The salivary IgA concentration of these patients was measured before and after 2 months of folic acid administration and compared with those of 10 healthy individuals.