ATEC23 Challenge: Automated prediction of treatment effectiveness in ovarian cancer using histopathological images.

Ovarian cancer, predominantly epithelial ovarian cancer (EOC), is a global health concern due to its high mortality rate. Despite the progress made during the last two decades in the surgery and chemotherapy of ovarian cancer, more than 70% of advanced patients are with recurrent cancer and disease. Bevacizumab is a humanized monoclonal antibody, which blocks VEGF signaling in cancer, inhibits angiogenesis and causes tumor shrinkage, and has been recently approved by the FDA as a monotherapy for advanced ovarian cancer in combination with chemotherapy.

Combining species distribution models and big datasets may provide finer assessments of snakebite impacts.

Background: Snakebite is a major poverty-related neglected tropical disease. An integrated scientific approach is needed to understand the dynamics of this important health issue. Our objective was to estimate snakebite occurrence in a tropical area by using a blend of ecological modelling and robust statistical analysis.

Assessment of Adverse Childhood Experiences in the South Bronx on the Risk of Developing Chronic Disease as Adults.

Background Adverse childhood experiences (ACEs) have a negative impact on health outcomes. Using a cross-sectional study design, our objective was to identify the prevalence of ACEs among residents of South Bronx and the increased relationship between such childhood stressors and the prevalence of both chronic disease and modifiable high-risk behavior in adulthood. Methods We recruited patients from a hospital-based, adult primary care clinic in the metropolitan area of the South Bronx.

Daily Life and Challenges Faced By Households With Permanent Childhood Developmental Disability in Rural Tanzania - A Qualitative Study.

Severe developmental disability in children affects the life of the child and entire household. We conducted a qualitative study to understand how caregivers manage severe developmental disabilities in children in rural Africa. Families and six children (out of 15 children) who had serious permanent sequelae from a cerebral infection in Handeni, Tanzania, were contacted and invited to a workshop to recount their experience living with severe developmental disabilities.

A Computational Framework for Studying Gut-Brain Axis in Autism Spectrum Disorder.

Introduction: The integrity of the intestinal epithelium is crucial for human health and is harmed in autism spectrum disorder (ASD). An aberrant gut microbial composition resulting in gut-derived metabolic toxins was found to damage the intestinal epithelium, jeopardizing tissue integrity. These toxins further reach the brain the gut-brain axis, disrupting the normal function of the brain.

A descriptive study of Forcefully Displaced Myanmar Nationals (FDMN) presenting for care at public health sector hospitals in Bangladesh.

Background: In 2017 hundreds of thousands of 'Rohingya' fled to camps for Forcefully Displaced Myanmar Nationals (FDMN) in Cox's Bazar, Bangladesh.

Objective: To describe the FDMNs presenting for care at public health facilities in Bangladesh so as to understand the health problems faced by the FDMNs and the burden on these public health facilities.

Methods: This study combined a retrospective review of existing hospital and clinic data with prospective surveillance in government health care centres.

A Rapid Assessment of Health Literacy and Health Status of Rohingya Refugees Living in Cox's Bazar, Bangladesh Following the August 2017 Exodus from Myanmar: A Cross-Sectional Study.

Background: A survey was conducted among Rohingya refugees to assess their overall health literacy and health status.

Methods: A questionnaire was developed to conduct face to face interviews among Rohingya refugees in Cox's Bazar, Bangladesh in November-December 2017. Families were selected using convenience sampling from four large refugee camps.

Artificial intelligence may offer insight into factors determining individual TSH level.

The factors that determine Serum Thyrotropin (TSH) levels have been examined through different methods, using different covariates. However, the use of machine learning methods has so far not been studied in population databases like NHANES (National Health and Nutritional Examination Survey) to predict TSH. In this study, we performed a comparative analysis of different machine learning methods like Linear regression, Random forest, Support vector machine, multilayer perceptron and stacking regression to predict TSH and classify individuals with normal, low and high TSH levels.

Qualitative study of knowledge, perception, behavior and barriers associated with cardiovascular disease risk among overweight and obese Hispanic taxi drivers of South Bronx, NYC.

Background: Taxi drivers are prone to developing cardiovascular disease (CVD) risk factors by adopting poor health behaviors due to their work environment. The population of Hispanic taxi drivers in inner city South Bronx, NYC, have not been studied. The goal of our qualitative study is to understand the perception, knowledge, behavior and barriers that influence CVD risk in overweight and obese inner-city Hispanic drivers.

Graphene/Nickel Oxide-Based Nanocomposite of Polyaniline with Special Reference to Ammonia Sensing.

Polyaniline@graphene/nickel oxide (Pani@GN/NiO), polyaniline/graphene (Pani/GN), and polyaniline/nickel oxide (Pani/NiO) nanocomposites and polyaniline (Pani) were successfully synthesized and tested for ammonia sensing. Pani@GN/NiO, Pani/NiO, Pani/GN, and Pani were characterized using X-ray diffraction, UV-vis spectroscopy, Raman spectroscopy, scanning electron microscopy, and transmission electron microscopy. The as-prepared materials were studied for comparative dc electrical conductivity and the change in their electrical conductivity on exposure to ammonia vapors followed by ambient air at room temperature.

The timing is right to end snakebite deaths in South Asia.

Regional collaboration is crucial to end preventable deaths and disability from snakebites in South Asia, say

Endodontic management of an unusual maxillary first molar with a single buccal root.

Aim: The aim of this clinical article is to describe the unusual anatomy that was detected in a maxillary first molar during routine endodontic treatment.

Background: Variation in Root and Root canal morphology especially in multirooted teeth presents a constant challenge for a clinician in their detection and management. The literature is replete with cases that have extra canal or Root but cases with fused Root and fewer numbers of canals are sparse.

Retinal changes in visceral leishmaniasis by retinal photography.

Background: In visceral leishmaniasis (VL), retinal changes have previously been noted but not described in detail and their clinical and pathological significance are unknown. A prospective observational study was undertaken in Mymensingh, Bangladesh aiming to describe in detail visible changes in the retina in unselected patients with VL.

Methods: Patients underwent assessment of visual function, indirect and direct ophthalmoscopy and portable retinal photography.

A study on delay in treatment of kala-azar patients in Bangladesh.

Visceral leishmaniasis (kala-azar) continues to be a major rural public health problem in Bangladesh. A cross-sectional study was carried out in two subdistricts of Mymensingh district from January 2006 to June 2007 to evaluate the delay kala-azar treatment. Suspected patients who attended to out patient department (OPD) were subjected to a dipstick test (RK39) for kala-azar.