Publications by authors named "Mohammad E Allaf"
Article Synopsis
- Indeterminate renal masses are often discovered incidentally through imaging, and Tc-sestamibi scans can help differentiate between oncocytomas and certain types of renal cell carcinomas, particularly chRCC, which may often be misclassified as false positives.
- A review of 18 patients with solitary tumors revealed that 72.2% of the tumors remained classified as chRCC, though some were reclassified into different categories, indicating a potential for misinterpretation in imaging.
- The findings suggest that the false-positive rate for chRCC on renal sestamibi scans may have been exaggerated, highlighting the need for further research to improve non-invasive assessment of indeterminate renal masses.
Vascular Expression of Prostate-specific Membrane Antigen (PSMA) in MiTF Family Translocation Renal Cell Carcinoma and Related Neoplasms.
Appl Immunohistochem Mol Morphol
September 2023
Multiple studies have demonstrated prostate-specific membrane antigen (PSMA) expression in the neo-vasculature of non-prostate tumors including clear cell renal cell carcinoma (ccRCC). However, PSMA expression in rare renal tumors including MiTF family translocation renal cell carcinoma has not been previously characterized. We examined PSMA expression by immunohistochemistry in a series of MiTF family translocation renal cell carcinomas as well as in several genetically related tumors including alveolar soft part sarcoma and PEComas with TFE3 rearrangements.
View Article and Find Full Text PDFObjective: PET imaging using radiotracers that target prostate-specific membrane antigen (PSMA) are increasingly being used in the evaluation of men with prostate cancer (PCa). It is therefore of increasing importance for imaging specialists to recognize potential pitfalls of this novel imaging technique. In this report, we describe a series of benign elastofibroma dorsi with uptake of the PSMA-targeted PET radiotracer F-DCFPyL.
View Article and Find Full Text PDFRenal cell carcinoma (RCC) is common with more than 60,000 new cases in the United States yearly. No curative therapies are available for metastatic RCC. Improved methods of imaging metastatic RCC would be of value in identifying sites of occult disease and potentially for judging response to therapy.
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