An analytical review of the therapeutic application of recent trends in MIL-based delivery systems in cancer therapy.

MILs (Materials Institute Lavoisier), as nanocarriers based on metal-organic frameworks (MOFs), are one of the most advanced drug delivery vehicles that are now a major part of cancer treatment research. This review article highlights the key features and components of MIL nanocarriers for the development and improvement of these nanocarriers for drug delivery. Surface coatings are one of the key components of MIL nanocarriers, which play the role of stabilizing the nanocarrier, pH-dependent drug release, increasing the half-life of the drug, and targeting the carrier.

Determination of BTEX Compounds in Contaminated Water Using the Novel Vacuum-Assisted-Total Vaporization SPME Method and GO-APTES Fiber.

A novel and reliable microextraction technique was used for the fast determination of benzene, toluene, ethylbenzene and xylenes (BTEX) from contaminated water without any extra steps for the preparation or extraction of the aqueous sample. Vacuum-assisted-total vaporization-solid-phase microextraction (SPME) eliminated one of the partitioning steps in conventional headspace SPME and caused an increase in the sensitivity and speed of the method. A home-made graphene oxide/3-aminopropyl-triethoxysilane nanocomposite SPME fiber was synthesized and used as the extraction phase for efficient extraction.

Evaluation of antioxidant and anti-ulcerogenic effects of Eremurus persicus (Jaub & Spach) Boiss leaf hydroalcoholic extract on ethanol-induced gastric ulcer in rats.

This study aimed to investigate the antioxidant and protective effect of E. persicus leaf hydroalcoholic extract (EPE) in preventing gastric ulcers induced by ethanol in rats. Wistar rats weighing 180-220 g were randomly divided into five groups.

A review of the biological and pharmacological activities of mesalazine or 5-aminosalicylic acid (5-ASA): an anti-ulcer and anti-oxidant drug.

Mesalazine, also known as 5-aminosalicylic acid (5-ASA), is a synthetic drug from the family of nonsteroidal anti-inflammatory drugs (NSAIDs) used for inflammatory diseases of the gastrointestinal tract. However, 5-ASA has also been used for various other diseases due to its pharmacological effects, but they are usually scattered across various publications, which may limit further research and clinical use of this drug. This review is a summary of published information on the biological and pharmacological effects of 5-ASA with the aim of identifying its anti-oxidant role and medicinal use.

Iranian plant : an overview of botany, traditional uses, phytochemistry and pharmacology.

commonly known as "Serish" is a valuable ornamental plant with culinary uses and also utilized in traditional medicine for treating Gastrointestinal diseases. This comprehensive study was performed to investigate the pharmacological and biological effects of and the compounds identified and isolated from it in order to encourage researchers to study it further. Despite the few number of studies on the ethnopharmacology of the plant , however studies conducted on either crude extracts, solvent fractions or isolated pure compounds from a varied range of biological effects comprising antibacterial, anti-fungal, anti-diabetic and etc.

Ameliorating and protective effects mesalazine on ethanol-induced gastric ulcers in experimental rats.

Gastric ulcer is a frequent gastrointestinal tract (GIT) disorder that affects about 10% of the world population. Drug candidates that can provide high efficacy and low toxicity are needed value for the prevention and treatment of gastric ulcers. The present study aimed to assess the protective effect of mesalazine against ethanol-induced gastric mucosal injury in rats.

An ultrasound-assisted pressure-regulated solid-phase microextraction setup for fast and sensitive analysis of volatile pollutants in contaminated soil.

Release of analytes from their native matrix and diffusion into the gas phase is the rate-limiting step for the sampling of volatiles in complex solid samples. This limitation is more serious in the solvent-less and solvent-free microextraction sampling strategies. In this research, a three-stage reinforced sampling strategy including high-pressure/sonication/low-pressure was introduced for fast and efficient release of analytes in soil samples.

Design and optimization of the VA-TV-SPME method for ultrasensitive determination of the PAHs in polluted water.

This paper describes how a novel and reliable alternative approach was developed for conventional solid-phase microextraction (SPME) sampling by total-vaporization of a sample under vacuum conditions. SPME sampling consists two stages of the equilibrium process, which take place between the sample/headspace and the headspace/fiber coating. In the total-vaporization SPME (TV-SPME) strategy, the first stage is omitted and analytes are directly partitioned between the headspace and fiber coating.