Publications by authors named "Mohammad Azimi-Alamouty"
Evaluation of the effect of an amniotic membrane derived bio-nano product (LifeCell) on human endometrial cells proliferation and gene expression: An in-vitro study.
Eur J Obstet Gynecol Reprod Biol
December 2024
Article Synopsis
- The study investigates the effects of LifeCell, a product from BioNano Technology, on the growth and receptivity of endometrial cells, which is crucial for successful assisted reproductive technology (ART).
- Results show that a 5% solution of LifeCell significantly boosts cell growth and enhances the expression of key genes related to endometrial receptivity, particularly FGF2 and CSF after 72 hours of co-culturing.
- The findings imply that LifeCell could be a viable treatment option for individuals facing infertility due to a thin endometrium that does not respond to other treatments.
Objectives: Early effective treatment and appropriate coverage are vital for full-thickness wounds. Amnion membrane-derived products have recently emerged in tissue engineering. However, the optimal concentration, carrier for controlled release, and handling have remained challenges.
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