Publications by Mohammad Amjad Hussain | LitMetric

Publications by authors named "Mohammad Amjad Hussain"

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A review on the functional characteristics of the c-Myeloproliferative Leukaemia (c-MPL) gene and its isoforms.

Mohammad Amjad Hussain Shankar Prasad Das Mithila Kulkarni Suparna Laha

Cell Oncol (Dordr)

October 2024

Article Synopsis

The c-MPL-TPO axis plays a key role in hematopoiesis by activating important signaling pathways like JAK/STAT, MAPK/ERK, and PIK3/AKT.
This research emphasizes the effects of c-MPL mutations on blood cell formation and highlights c-MPL's involvement in diseases beyond blood disorders, such as Unstable Angina and DNA damage repair.
The study suggests the potential of c-MPL as a therapeutic target and biomarker for cancer-related issues, advocating for further exploration of its isoforms for future gene-therapy applications.

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