A review of chitosan-based multifunctional nanocomposites for drug/gene/protein delivery and gene therapy in cancer treatments: Promises, challenges and outlooks.

This study provides a comprehensive examination of chitosan-based multifunctional nanocomposites and their extensive applications in drug/gene/protein delivery, tissue engineering and cancer therapy. As a natural polymer with eco-friendly characteristics and both antimicrobial and anti-cancer properties, chitosan has garnered attention in numerous medical and pharmaceutical domains. The research explores diverse chitosan nanocomposites, including those incorporating magnetic nanoparticles, carbon nanotubes, and clay- and alginate-based nanocomposites.